The effect of COVID-19 on absolute neutrophil counts in patients taking clozapine.
Ther Adv Psychopharmacol
; 10: 2045125320940935, 2020.
Article
in English
| MEDLINE | ID: covidwho-667342
ABSTRACT
Clozapine is associated with haematological side effects, including neutropaenia, which can signal impending life-threatening agranulocytosis. Patients with COVID-19 infection frequently experience lymphopaenia, but not neutropaenia. We present 13 patients established on clozapine who developed COVID-19 infection. There were no significant differences in total white cell or neutrophil counts between pre-COVID-19, intra-COVID-19 or post-COVID-19 periods. We therefore suggest that patients who develop COVID-19 should generally have their clozapine treatment continued. Patients taking clozapine who develop neutroapaenia during COVID-19 infection should be investigated and monitored as in normal practice, because changes in neutrophil counts cannot be assumed to be due to the viral infection.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
Topics:
Long Covid
Language:
English
Journal:
Ther Adv Psychopharmacol
Year:
2020
Document Type:
Article
Affiliation country:
2045125320940935
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