A Global lmmunological Observatory to meet a time of pandemics.

Mina, Michael J; Metcalf, C Jessica E; McDermott, Adrian B; Douek, Daniel C; Farrar, Jeremy; Grenfell, Bryan T

Mina, Michael J; Metcalf, C Jessica E; McDermott, Adrian B; Douek, Daniel C; Farrar, Jeremy; Grenfell, Bryan T.

Mina MJ; Center for Communicable Disease Dynamics, Department of Epidemiology, and Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, United States.
Metcalf CJE; Department of Pathology, Brigham and Women's Hospital, Boston, United States.
McDermott AB; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States.
Douek DC; Woodrow Wilson School, Princeton University, Princeton, United States.
Farrar J; Vaccine Research Center, National Institutes of Health, Bethesda, United States.
Grenfell BT; Vaccine Research Center, National Institutes of Health, Bethesda, United States.

Elife ; 92020 06 08.

Article in English | MEDLINE | ID: covidwho-1497819

ABSTRACT

ABSTRACT

SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise.

Subject(s)

Communicable Disease Control/organization & administration; Communicable Diseases, Emerging/prevention & control; Coronavirus Infections/epidemiology; Disaster Planning/organization & administration; Global Health; International Cooperation; Pandemics/prevention & control; Pneumonia, Viral/epidemiology; Population Surveillance; Animals; Anti-Infective Agents; COVID-19; Climate Change; Cohort Studies; Communicable Disease Control/methods; Communicable Diseases, Emerging/diagnosis; Communicable Diseases, Emerging/epidemiology; Communicable Diseases, Emerging/immunology; Drug Development; Forecasting; Global Health/trends; Humans; Interdisciplinary Communication; Mass Screening/organization & administration; Models, Animal; Population Surveillance/methods; Serologic Tests; Vaccines; Weather; Zoonoses

Keywords

COVID-19; SARS-CoV-2; epidemiology; global health; global surveillance; human; immunology; inflammation; pandemic; science forum; serology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Communicable Disease Control / Population Surveillance / Global Health / Coronavirus Infections / Communicable Diseases, Emerging / Disaster Planning / Pandemics / International Cooperation Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Animals / Humans Language: English Year: 2020 Document Type: Article Affiliation country: ELife.58989

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