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Sars-CoV-2 in pregnancy: Why is it better than expected?
Ghi, Tullio; di Pasquo, Elvira; Mekinian, Arsene; Calza, Leonardo; Frusca, Tiziana.
  • Ghi T; Department of Obstetrics and Gynecology, University of Parma, Parma, Italy. Electronic address: tullio.ghi@unipr.it.
  • di Pasquo E; Department of Obstetrics and Gynecology, University of Parma, Parma, Italy.
  • Mekinian A; Department of Internal Medicine, Referral Center for Autoimmune Diseases, Saint Antoine Hospital, Sorbonne University, Paris, France.
  • Calza L; Unit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, "Alma Mater Studiorum" University of Bologna, Bologna, Italy.
  • Frusca T; Department of Obstetrics and Gynecology, University of Parma, Parma, Italy.
Eur J Obstet Gynecol Reprod Biol ; 252: 476-478, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-670424
ABSTRACT
Since the outbreak of Coronavirus disease in December 2019, information specific to pregnancy remains limited and controversial. Based on data from previous reports, it has been noticed that contrary to prior pandemics such as SARS, MERS and H1N1 and although pregnancy is usually considered as a condition of high susceptibility to viral infections, new SARS-CoV2 infection seems to have a more benign clinical course when affecting pregnant women. We speculate that during pregnancy the physiological "silencing" of the Th1 pro-inflammatory response may blunt the cytokines storm which is thought to play a key-role in the pathogenesis of the severe complications of Covid-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pregnancy Complications, Infectious / Coronavirus Infections / Betacoronavirus Type of study: Prognostic study Limits: Female / Humans / Pregnancy Language: English Journal: Eur J Obstet Gynecol Reprod Biol Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pregnancy Complications, Infectious / Coronavirus Infections / Betacoronavirus Type of study: Prognostic study Limits: Female / Humans / Pregnancy Language: English Journal: Eur J Obstet Gynecol Reprod Biol Year: 2020 Document Type: Article