Your browser doesn't support javascript.
N-acetycysteine: A potential therapeutic agent in COVID-19 infection.
Jaiswal, N; Bhatnagar, M; Shah, H.
  • Jaiswal N; Animal Biotech and Molecular Neuroscience, Dept of Zoology, MLS University, Udaipur, India. Electronic address: jaisneha411@gmail.com.
  • Bhatnagar M; Ex Dean and CHAIRMAN Faculty of Science, Dept of Zoology, MLS University, Udaipur, India.
  • Shah H; Head Dept. of Microbiology, Index Medical College, Indore, India.
Med Hypotheses ; 144: 110133, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-670653
Semantic information from SemMedBD (by NLM)
1. Lung Injury CAUSES Chronic Obstructive Airway Disease
Subject
Lung Injury
Predicate
CAUSES
Object
Chronic Obstructive Airway Disease
2. Virus Diseases CAUSES Imbalance
Subject
Virus Diseases
Predicate
CAUSES
Object
Imbalance
3. Pharmaceutical Preparations INHIBITS Reactive Oxygen Species
Subject
Pharmaceutical Preparations
Predicate
INHIBITS
Object
Reactive Oxygen Species
4. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
5. Lung Injury CAUSES Chronic Obstructive Airway Disease
Subject
Lung Injury
Predicate
CAUSES
Object
Chronic Obstructive Airway Disease
6. Virus Diseases CAUSES Imbalance
Subject
Virus Diseases
Predicate
CAUSES
Object
Imbalance
7. Pharmaceutical Preparations INHIBITS Reactive Oxygen Species
Subject
Pharmaceutical Preparations
Predicate
INHIBITS
Object
Reactive Oxygen Species
8. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
COVID-19 is an overwhelming pandemic which has shattered the whole world. Lung injury being the main clinical manifestation, it is likely to cause COPD (chronic obstructive pulmonary disease) and ARDS (acute respiratory distress syndrome). The possible cause behind this might be redox imbalance due to viral infection. Elevation in Glutathione (GSH) levels by administration of its promolecule might be effective. N-acetylcysteine is one such drug with potency to scavenge Reactive Oxygen Species, least side effects, and an effective precursor of glutathione. Consequently we hypothesize that N-acetylcysteine along with the conventional treatment may be treated as a potential therapeutic solution in cases of COVID-19 patients.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Acetylcysteine / Glutathione Type of study: Prognostic study Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Acetylcysteine / Glutathione Type of study: Prognostic study Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article