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N-acetycysteine: A potential therapeutic agent in COVID-19 infection.
Jaiswal, N; Bhatnagar, M; Shah, H.
  • Jaiswal N; Animal Biotech and Molecular Neuroscience, Dept of Zoology, MLS University, Udaipur, India. Electronic address: jaisneha411@gmail.com.
  • Bhatnagar M; Ex Dean and CHAIRMAN Faculty of Science, Dept of Zoology, MLS University, Udaipur, India.
  • Shah H; Head Dept. of Microbiology, Index Medical College, Indore, India.
Med Hypotheses ; 144: 110133, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-670653
ABSTRACT
COVID-19 is an overwhelming pandemic which has shattered the whole world. Lung injury being the main clinical manifestation, it is likely to cause COPD (chronic obstructive pulmonary disease) and ARDS (acute respiratory distress syndrome). The possible cause behind this might be redox imbalance due to viral infection. Elevation in Glutathione (GSH) levels by administration of its promolecule might be effective. N-acetylcysteine is one such drug with potency to scavenge Reactive Oxygen Species, least side effects, and an effective precursor of glutathione. Consequently we hypothesize that N-acetylcysteine along with the conventional treatment may be treated as a potential therapeutic solution in cases of COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acetylcysteine / COVID-19 Drug Treatment / Glutathione Type of study: Prognostic study Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acetylcysteine / COVID-19 Drug Treatment / Glutathione Type of study: Prognostic study Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article