Your browser doesn't support javascript.
Cardiac arrhythmias in patients with COVID-19.
Wang, Yueying; Wang, Zhaojia; Tse, Gary; Zhang, Lin; Wan, Elaine Y; Guo, Yutao; Lip, Gregory Y H; Li, Guangping; Lu, Zhibing; Liu, Tong.
  • Wang Y; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin People's Republic of China.
  • Wang Z; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin People's Republic of China.
  • Tse G; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin People's Republic of China.
  • Zhang L; Department of Cardiology Zhongnan Hospital of Wuhan University Wuhan People's Republic of China.
  • Wan EY; Division of Cardiology Department of Medicine Vagelos College of Physicians and Surgeons Columbia University New York NY USA.
  • Guo Y; Medical School of Chinese PLA Department of Cardiology Chinese PLA General Hospital Beijing China.
  • Lip GYH; Medical School of Chinese PLA Department of Cardiology Chinese PLA General Hospital Beijing China.
  • Li G; Liverpool Centre for Cardiovascular Sciences University of Liverpool and Liverpool Heart & Chest Hospital Liverpool UK.
  • Lu Z; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin People's Republic of China.
  • Liu T; Department of Cardiology Zhongnan Hospital of Wuhan University Wuhan People's Republic of China.
J Arrhythm ; 36(5): 827-836, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-676847
ABSTRACT
The emergence of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major global public health concern. Although SARS-CoV-2 causes primarily respiratory problems, concurrent cardiac injury cannot be ignored since it may be an independent predictor for adverse outcomes. Cardiac arrhythmias are often observed in patients with COVID-19, especially in severe cases, and more likely contribute to the high risk of adverse outcomes. Arrhythmias should be regarded as one of the main complications of COVID-19. Mechanistically, a number of ion channels can be adversely affected in COVID-19, leading to alterations in cardiac conduction and/or repolarization properties, as well as calcium handling, which can predispose to cardiac arrhythmogenesis. In addition, several antimicrobials that are currently used as potential therapeutic agents for COVID-19, such as chloroquine, hydroxychloroquine and azithromycin, have uncertain benefit, and yet may induce electrocardiographic QT prolongation with potential ventricular pro-arrhythmic effects. Continuous electrocardiogram monitoring, accurate and prompt recognition of arrhythmias are important. The present review focuses on cardiac arrhythmias in patients with COVID-19, its underlying mechanisms, and proposed preventive and therapeutic strategies.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: J Arrhythm Year: 2020 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: J Arrhythm Year: 2020 Document Type: Article