Progress in SARS and MERS vaccines: lessons for the development of COVID-19 vaccine

ABSTRACT

Safe and effective vaccines are urgently needed to prevent and control the outbreak of COVID-19. 2019-nCoV belongs to the genus Betacoronavirus like severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Here we summarized the current progress and problems in the development of vaccines against SARS-CoV and MERS-CoV in order to provide reference for COVID-19 vaccine development.