Relating angiotensin-converting enzyme inhibitors or angiotensin receptor blockers with incidence or mortality of COVID-19.

Wong, Martin C S; Wong, Sunny; Huang, Junjie; Yan, Bryan

Wong, Martin C S; Wong, Sunny; Huang, Junjie; Yan, Bryan.

Wong MCS; JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Wong S; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Huang J; JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Yan B; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.

ESC Heart Fail ; 7(5): 3119-3123, 2020 10.

Article in English | MEDLINE | ID: covidwho-679971

ABSTRACT

ABSTRACT

The present Perspective examined the latest evidence on the association between the use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) and the incidence/mortality of coronavirus disease 2019 (COVID-19). Our critical appraisal from existing literature does not support discontinuation of ACEIs/ARBs in clinical practice as there is absence of solid evidence. However, we do recommend future research perspective in formulation and implementation of practice-changing guidelines.

Subject(s)

Angiotensin Receptor Antagonists/adverse effects; Angiotensin-Converting Enzyme Inhibitors/adverse effects; Coronavirus Infections/drug therapy; Pandemics/statistics & numerical data; Pneumonia, Viral/drug therapy; Severe Acute Respiratory Syndrome/mortality; Adult; Aged; Angiotensin Receptor Antagonists/therapeutic use; Angiotensin-Converting Enzyme Inhibitors/therapeutic use; COVID-19; Cause of Death; Coronavirus Infections/mortality; Female; Hospital Mortality/trends; Humans; Incidence; Male; Middle Aged; Pneumonia, Viral/mortality; Prognosis; Risk Assessment; Severe Acute Respiratory Syndrome/drug therapy; Survival Analysis

Keywords

Angiotensin receptor blocker; Angiotensin-converting enzyme inhibitor; COVID-19; Mortality; Severity

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Angiotensin-Converting Enzyme Inhibitors / Coronavirus Infections / Severe Acute Respiratory Syndrome / Angiotensin Receptor Antagonists / Pandemics Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: ESC Heart Fail Year: 2020 Document Type: Article Affiliation country: Ehf2.12952

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google