Your browser doesn't support javascript.
Role of extracorporeal membrane oxygenation in COVID-19: A systematic review.
Haiduc, Ana Alina; Alom, Samiha; Melamed, Naomi; Harky, Amer.
  • Haiduc AA; Medical School, St George's, University of London, London, UK.
  • Alom S; Medical School, St George's, University of London, London, UK.
  • Melamed N; School of Public Health, Imperial College London, London, UK.
  • Harky A; Medical School, St George's, University of London, London, UK.
J Card Surg ; 35(10): 2679-2687, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-680252
ABSTRACT

OBJECTIVE:

We aimed to examine the literature evidence behind using extracorporeal membrane oxygenation in COVID-19 patients in a systematic review manner.

METHODS:

We conducted a systematic review using Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. A comprehensive literature search was conducted on Global Health Medline, EMBASE, and Cochrane databases using keywords and MeSH terms to identify articles pertaining to extracorporeal membrane oxygenation (ECMO) and Coronavirus disease 2019 (COVID-19). A narrative synthesis was then undertaken to identify the key themes.

RESULTS:

A total of 25 articles met the inclusion criteria of this systematic review. Three main themes were identified following the data extraction (a) evidence against/inconclusive regarding ECMO for COVID-19, (b) evidence supporting ECMO for COVID-19, and finally (c) VV-ECMO and VA-ECMO. After combining the data, there were 3428 patients diagnosed with COVID-19 and 95 ECMO-associated deaths (19.83%).

CONCLUSION:

Our study highlights the paucity of evidence and the need for further data to consolidate the efficacy of ECMO in improving patient outcomes. Although ECMO has been shown to be beneficial in a selected group of patients, the recuperative effects of ECMO remain inconclusive. We must ensure that risk-benefit analysis for each candidate is conducted thoroughly so that patients that have increased probability of survival can benefit from this scarce resource.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Extracorporeal Membrane Oxygenation / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Limits: Humans Language: English Journal: J Card Surg Journal subject: Cardiology Year: 2020 Document Type: Article Affiliation country: Jocs.14879

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Extracorporeal Membrane Oxygenation / Coronavirus Infections / Pandemics / Betacoronavirus Type of study: Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Limits: Humans Language: English Journal: J Card Surg Journal subject: Cardiology Year: 2020 Document Type: Article Affiliation country: Jocs.14879