Hepatology Consultants Often Disagree on Etiology of Abnormal Liver Biochemistries in COVID-19 but Agree on Management.
Dig Dis Sci
; 66(6): 1852-1854, 2021 06.
Article
in English
| MEDLINE | ID: covidwho-684223
ABSTRACT
BACKGROUND:
Coronavirus disease 2019 (COVID-19) is associated with elevated liver biochemistries in approximately half of hospitalized patients, with many possible etiologies.AIM:
To assess agreement on the etiology of abnormal liver biochemistries and diagnostic recommendations in COVID-19.METHODS:
Twenty hepatology consultations were reviewed by three senior hepatologists who provided a differential diagnosis and diagnostic recommendations. Kappa agreement on the primary etiology was calculated.RESULTS:
Kappa agreement between hepatologists on the primary etiology of elevated liver biochemistries was 0.10 (p = 0.03). Agreement was greater around drug-induced liver injury 0.51 (p < 0.0001) and SARS-CoV-2-related liver injury 0.17 (p = 0.03). Serial liver biochemistries were recommended in all consultations over other evaluations.CONCLUSION:
In COVID-19, elevated liver biochemistries present a diagnostic challenge and can often be monitored conservatively.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Referral and Consultation
/
Gastroenterologists
/
COVID-19
/
Liver
/
Liver Diseases
/
Liver Function Tests
Type of study:
Diagnostic study
/
Etiology study
/
Experimental Studies
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Dig Dis Sci
Year:
2021
Document Type:
Article
Affiliation country:
S10620-020-06495-w
Similar
MEDLINE
...
LILACS
LIS