Neurological Complications in COVID-19 Patients and its Implications for Associated Mortality.
Curr Neurovasc Res
; 17(4): 522-530, 2020.
Article
in English
| MEDLINE | ID: covidwho-688646
ABSTRACT
Coronavirus is an enveloped, non-segmented, positive-polarity and single-stranded RNA virus. It has four types of genera that infect mammals and birds, with only alpha and beta types found to affect humans with varying severity. A specific clade of beta coronaviruses is reported as lethal zoonotic viruses and has created major epidemic troubles, starting with the severe acute respiratory syndrome (SARS) in 2002, then the Middle East respiratory syndrome (MERS) in 2012, and lastly Coronavirus Disease 2019 (COVID-19) in 2019. However, many neurological complications reported in COVID-19 patients have highlighted a critical pattern of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Awareness of such an association could create new insight to consider neurological manifestations as a COVID-19 differential diagnosis during the pandemic period of COVID-19 to avoid delayed diagnosis and prevent further transmission. This mini-review aims to collect the current knowledge regarding the mechanism behind the neuroinvasive capacity of SARS-CoV-2, to summarize the common documented neurological symptoms and associated complications in COVID-19 patients, and to review the impact of neurological manifestations on COVID-19 mortality.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Coronavirus Infections
/
SARS-CoV-2
/
COVID-19
/
Nervous System Diseases
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Animals
/
Humans
Language:
English
Journal:
Curr Neurovasc Res
Journal subject:
Vascular Diseases
/
Neurology
Year:
2020
Document Type:
Article
Affiliation country:
1567202617666200727124704
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