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A Comparison of Clinical Characteristics and Outcomes in Elderly and Younger Patients with COVID-19.
Song, Jia; Hu, Weihang; Yu, Yihua; Shen, Xin; Wang, Yueben; Yan, Jin; Yang, Xianghong; Gong, Shijin; Wang, Minjia.
  • Song J; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Hu W; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Yu Y; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Shen X; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Wang Y; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Yan J; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Yang X; Intensive Care Unit, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China (mainland).
  • Gong S; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
  • Wang M; Intensive Care Unit, Zhejiang Hospital, Hangzhou, Zhejiang, China (mainland).
Med Sci Monit ; 26: e925047, 2020 Jul 28.
Article in English | MEDLINE | ID: covidwho-689085
ABSTRACT
BACKGROUND The aim of this study was to describe the clinical characteristics and outcomes of patients with coronavirus disease 2019 (COVID-19) and compare these parameters in an elderly group with those in a younger group. MATERIAL AND METHODS This retrospective, single-center observational study included 69 hospitalized patients with laboratory-confirmed COVID-19 from a tertiary hospital in Wuhan, China, between January 14, 2020, and February 26, 2020. Epidemiological, demographic, clinical, and laboratory data, as well as treatments, complications, and outcomes were extracted from electronic medical records and compared between elderly patients (aged ≥60 years) and younger patients (aged <60 years). Patients were followed until March 19, 2020. RESULTS Elderly patients had more complications than younger patients, including acute respiratory distress syndrome (ARDS; 9/25, 36% vs. 5/44, 11.4%) and cardiac injury (7/25, 28% vs. 1/44, 2.3%), and they were more likely to be admitted to the intensive care unit (6/25, 24% vs. 2/44, 4.5%). As of March 19, 2020, 60/69 (87%) of the patients had been discharged, 6/69 (8.7%) had died, and 3/69 (4.3%) remained in the hospital. Of those who were discharged or died, the median duration of hospitalization was 13.5 days (interquartile range, 10-18 days). CONCLUSIONS Elderly patients with confirmed COVID-19 were more likely to develop ARDS and cardiac injury than younger patients and were more likely to be admitted to the intensive care unit. In addition to routine monitoring and respiratory support, cardiac monitoring and supportive care should be a focus in elderly patients with COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Age Factors / Coronavirus Infections / Pandemics / Heart Diseases Type of study: Observational study / Prognostic study Topics: Long Covid Country/Region as subject: Asia Language: English Journal: Med Sci Monit Journal subject: Medicine Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Age Factors / Coronavirus Infections / Pandemics / Heart Diseases Type of study: Observational study / Prognostic study Topics: Long Covid Country/Region as subject: Asia Language: English Journal: Med Sci Monit Journal subject: Medicine Year: 2020 Document Type: Article