Eosinophil-Derived Neurotoxin and Respiratory Tract Infection and Inflammation: Implications for COVID-19 Management.

Dosanjh, Amrita

Dosanjh, Amrita.

Dosanjh A; Department of Pediatrics RCHSD, Pediatric Respiratory, San Diego, California, USA.

J Interferon Cytokine Res ; 40(9): 443-445, 2020 09.

Article in English | MEDLINE | ID: covidwho-690435

ABSTRACT

ABSTRACT

The current pandemic of COVID-19 and the identification of accessible biomarkers of disease progression is of clinical importance in the management of this novel and serious disease. This study was completed to provide information regarding 1 possible uniquely upregulated marker in this illness, eosinophil-derived neurotoxin (EDN-1). A literature search was undertaken to provide medical data regarding EDN-1 as a biomarker in the clinical setting. The literature identified was further analyzed to identify its use in the clinical setting of viral disease and asthma.

Subject(s)

Alveolar Epithelial Cells/metabolism; Coronavirus Infections/pathology; Eosinophil-Derived Neurotoxin/metabolism; Pneumonia, Viral/pathology; Betacoronavirus; Biomarkers/analysis; COVID-19; Cytokine Release Syndrome/pathology; Eosinophils/metabolism; Humans; Pandemics; SARS-CoV-2; Transcriptome/genetics

Keywords

COVID-19; acute respiratory distress syndrome; biomarker; eosinophil-derived neurotoxin

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Eosinophil-Derived Neurotoxin / Alveolar Epithelial Cells Type of study: Prognostic study Limits: Humans Language: English Journal: J Interferon Cytokine Res Journal subject: Allergy and Immunology Year: 2020 Document Type: Article Affiliation country: Jir.2020.0066

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