Your browser doesn't support javascript.
Neuropathogenesis of SARS-CoV-2 infection.
Khan, Shumayila; Gomes, James.
  • Khan S; Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, New Delhi, India.
  • Gomes J; Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, New Delhi, India.
Elife ; 92020 07 30.
Article in English | MEDLINE | ID: covidwho-690669
ABSTRACT
The COVID-19 pandemic caused by the SARS-CoV-2 has recently emerged as a serious jolt to human life and economy. Initial knowledge established pulmonary complications as the chief symptom, however, the neurological aspect of the disease is also becoming increasingly evident. Emerging reports of encephalopathies and similar ailments with the detection of the virus in the CSF has elicited an urgent need for investigating the possibility of neuroinvasiveness of the virus, which cannot be ruled out given the expression of low levels of ACE2 receptors in the brain. Sensory impairments of the olfactory and gustatory systems have also been reported in a large proportion of the cases, indicating the involvement of the peripheral nervous system. Hence, the possibility of neurological damage caused by the virus demands immediate attention and investigation of the mechanisms involved, so as to customize the treatment of patients presenting with neurological complications.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Nervous System Diseases Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: ELife.59136

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Nervous System Diseases Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: ELife.59136