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Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design.
Lin, Sheng; Chen, Hua; Ye, Fei; Chen, Zimin; Yang, Fanli; Zheng, Yue; Cao, Yu; Qiao, Jingxin; Yang, Shengyong; Lu, Guangwen.
  • Lin S; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Chen H; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Ye F; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Chen Z; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Yang F; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Zheng Y; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Cao Y; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Qiao J; Disaster Medicine Center, West China Hospital, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Yang S; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
  • Lu G; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041, Chengdu, Sichuan, China.
Signal Transduct Target Ther ; 5(1): 131, 2020 07 29.
Article in English | MEDLINE | ID: covidwho-690769

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Viral Nonstructural Proteins / Coronavirus Infections / Viral Regulatory and Accessory Proteins / Betacoronavirus Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-00241-4

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Viral Nonstructural Proteins / Coronavirus Infections / Viral Regulatory and Accessory Proteins / Betacoronavirus Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-00241-4