Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.

Monneret, Guillaume; de Marignan, Donatien; Coudereau, Rémy; Bernet, Céline; Ader, Florence; Frobert, Emilie; Gossez, Morgane; Viel, Sébastien; Venet, Fabienne; Wallet, Florent

Monneret, Guillaume; de Marignan, Donatien; Coudereau, Rémy; Bernet, Céline; Ader, Florence; Frobert, Emilie; Gossez, Morgane; Viel, Sébastien; Venet, Fabienne; Wallet, Florent.

Monneret G; Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France. guillaume.monneret@chu-lyon.fr.
de Marignan D; Hospices Civils de Lyon, Lyon-Sud University Hospital, Medical Intensive Care Unit, Lyon, France.
Coudereau R; Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France.
Bernet C; Hospices Civils de Lyon, Lyon-Sud University Hospital, Medical Intensive Care Unit, Lyon, France.
Ader F; Hospices Civils de Lyon, Department of infectious Diseases, North University Hospital, Lyon, France.
Frobert E; International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon, France.
Gossez M; International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon, France.
Viel S; Hospices Civils de Lyon, Department of Virology, Infective Agents Institute, North University Hospital, Lyon, France.
Venet F; Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France.
Wallet F; International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon, France.

Cell Mol Immunol ; 17(9): 1001-1003, 2020 09.

Article in English | MEDLINE | ID: covidwho-690856

Subject(s)

Betacoronavirus/pathogenicity; Coronavirus Infections/immunology; Immunologic Factors/therapeutic use; Interleukin-7/therapeutic use; Lymphopenia/immunology; Pneumonia, Viral/immunology; Severe Acute Respiratory Syndrome/immunology; Acute Kidney Injury/diagnosis; Acute Kidney Injury/pathology; Aged; Anti-Bacterial Agents/therapeutic use; Antifungal Agents/therapeutic use; Betacoronavirus/immunology; COVID-19; Compassionate Use Trials; Coronavirus Infections/drug therapy; Coronavirus Infections/genetics; Coronavirus Infections/virology; Critical Illness; Fatal Outcome; Humans; Intensive Care Units; Lymphopenia/drug therapy; Lymphopenia/genetics; Lymphopenia/virology; Male; Pandemics; Pneumonia, Ventilator-Associated/diagnosis; Pneumonia, Ventilator-Associated/drug therapy; Pneumonia, Ventilator-Associated/etiology; Pneumonia, Ventilator-Associated/pathology; Pneumonia, Viral/drug therapy; Pneumonia, Viral/genetics; Pneumonia, Viral/virology; Respiration, Artificial/adverse effects; SARS-CoV-2; Severe Acute Respiratory Syndrome/drug therapy; Severe Acute Respiratory Syndrome/genetics; Severe Acute Respiratory Syndrome/virology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Interleukin-7 / Coronavirus Infections / Severe Acute Respiratory Syndrome / Betacoronavirus / Immunologic Factors / Lymphopenia Type of study: Case report / Diagnostic study / Prognostic study / Randomized controlled trials Language: English Journal: Cell Mol Immunol Journal subject: Allergy and Immunology Year: 2020 Document Type: Article Affiliation country: S41423-020-0516-6

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