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Amiodarone in the COVID-19 Era: Treatment for Symptomatic Patients Only, or Drug to Prevent Infection?
Sanchis-Gomar, Fabian; Lavie, Carl J; Morin, Daniel P; Perez-Quilis, Carme; Laukkanen, Jari A; Perez, Marco V.
  • Sanchis-Gomar F; Department of Physiology, Faculty of Medicine, INCLIVA Biomedical Research Institute, University of Valencia, Av. Blasco Ibáñez, 15, 46010, Valencia, Spain. fabian.sanchis@uv.es.
  • Lavie CJ; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA. fabian.sanchis@uv.es.
  • Morin DP; John Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA, USA.
  • Perez-Quilis C; John Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA, USA.
  • Laukkanen JA; Department of Physiology, Faculty of Medicine, INCLIVA Biomedical Research Institute, University of Valencia, Av. Blasco Ibáñez, 15, 46010, Valencia, Spain.
  • Perez MV; Institute of Clinical Medicine, Department of Medicine, University of Eastern Finland, Kuopio, Finland.
Am J Cardiovasc Drugs ; 20(5): 413-418, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-691058
ABSTRACT
Amiodarone, one of the most widely prescribed antiarrhythmic drugs to treat both ventricular and supraventricular arrhythmias, has been identified as a candidate drug for use against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We present the rationale of using amiodarone in the COVID-19 scenario, as well as whether or not amiodarone administration represents a potential strategy to prevent SARS-CoV-2 infection, rather than simply used to treat patients already symptomatic and/or with severe coronavirus disease 2019 (COVID-19), based on current evidence.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Arrhythmias, Cardiac / Coronavirus Infections / Pandemics / Betacoronavirus / Amiodarone Type of study: Prognostic study Limits: Humans Language: English Journal: Am J Cardiovasc Drugs Journal subject: Vascular Diseases / Cardiology / Drug Therapy Year: 2020 Document Type: Article Affiliation country: S40256-020-00429-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Arrhythmias, Cardiac / Coronavirus Infections / Pandemics / Betacoronavirus / Amiodarone Type of study: Prognostic study Limits: Humans Language: English Journal: Am J Cardiovasc Drugs Journal subject: Vascular Diseases / Cardiology / Drug Therapy Year: 2020 Document Type: Article Affiliation country: S40256-020-00429-7