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Myricetin bioactive effects: moving from preclinical evidence to potential clinical applications.
Taheri, Yasaman; Suleria, Hafiz Ansar Rasul; Martins, Natália; Sytar, Oksana; Beyatli, Ahmet; Yeskaliyeva, Balakyz; Seitimova, Gulnaz; Salehi, Bahare; Semwal, Prabhakar; Painuli, Sakshi; Kumar, Anuj; Azzini, Elena; Martorell, Miquel; Setzer, William N; Maroyi, Alfred; Sharifi-Rad, Javad.
  • Taheri Y; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Suleria HAR; Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Martins N; Department of Agriculture and Food Systems, The University of Melbourne, Melbourne, Australia.
  • Sytar O; Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
  • Beyatli A; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135, Porto, Portugal.
  • Yeskaliyeva B; Department of Plant Biology Department, Taras Shevchenko National University of Kyiv, Institute of Biology, Volodymyrska str., 64, Kyiv, 01033, Ukraine.
  • Seitimova G; Department of Plant Physiology, Slovak University of Agriculture, Nitra, A. Hlinku 2, 94976, Nitra, Slovak Republic.
  • Salehi B; Department of Medicinal and Aromatic Plants, University of Health Sciences, 34668, Istanbul, Turkey.
  • Semwal P; Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
  • Painuli S; Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
  • Kumar A; Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran. bahar.salehi007@gmail.com.
  • Azzini E; Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran. bahar.salehi007@gmail.com.
  • Martorell M; Department of Biotechnology, Graphic Era University, Dehradun, Uttarakhand, 248001, India. semwal.prabahakar@gmail.com.
  • Setzer WN; Uttarakhand State Council for Science and Technology, Vigyan Dham, Dehradun, Uttarakhand, 248007, India. semwal.prabahakar@gmail.com.
  • Maroyi A; Department of Biotechnology, Graphic Era University, Dehradun, Uttarakhand, 248001, India.
  • Sharifi-Rad J; Himalayan Environmental Studies and Conservation Organization, Prem Nagar, Dehradun, Uttarakhand, 248001, India.
BMC Complement Med Ther ; 20(1): 241, 2020 Aug 01.
Article in English | MEDLINE | ID: covidwho-692710
ABSTRACT
Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Flavonoids / Dietary Supplements Type of study: Experimental Studies / Prognostic study Topics: Traditional medicine Limits: Humans Language: English Journal: BMC Complement Med Ther Year: 2020 Document Type: Article Affiliation country: S12906-020-03033-z

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Flavonoids / Dietary Supplements Type of study: Experimental Studies / Prognostic study Topics: Traditional medicine Limits: Humans Language: English Journal: BMC Complement Med Ther Year: 2020 Document Type: Article Affiliation country: S12906-020-03033-z