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Management of primary hepatic malignancies during the COVID-19 pandemic: recommendations for risk mitigation from a multidisciplinary perspective.
Barry, Aisling; Apisarnthanarax, Smith; O'Kane, Grainne M; Sapisochin, Gonzalo; Beecroft, Robert; Salem, Riad; Yoon, Sang Min; Lim, Young-Suk; Bridgewater, John; Davidson, Brian; Scorsetti, Marta; Solbiati, Luigi; Diehl, Adam; Schuffenegger, Pablo Munoz; Sham, Jonathan G; Cavallucci, David; Galvin, Zita; Dawson, Laura A; Hawkins, Maria A.
  • Barry A; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada. Electronic address: aisling.barry@rmp.uhn.ca.
  • Apisarnthanarax S; Seattle Cancer Care Alliance, and Department of Radiation Oncology, University of Washington, Seattle, WA, USA.
  • O'Kane GM; Department of Medical Oncology and Haematology, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
  • Sapisochin G; Princess Margaret Cancer Centre, and Department of Surgery, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
  • Beecroft R; Department of Medical Imaging, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
  • Salem R; Department of Interventional Radiology, Northwestern University, Chicago, IL, USA.
  • Yoon SM; Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Lim YS; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Bridgewater J; UCL Cancer Institute, University College London, London, UK.
  • Davidson B; Department of Surgical Biotechnology, UCL Division of Surgery and Interventional Science, University College London, London, UK.
  • Scorsetti M; Radiotherapy and Radiosurgery Department, Humanitas Clinical and Research Center, IRCCS Humanitas Research Hospital, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy.
  • Solbiati L; Radiology Department, Humanitas Clinical and Research Center, IRCCS Humanitas Research Hospital, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy.
  • Diehl A; Department of Medical Oncology, University of Washington, Seattle, WA, USA.
  • Schuffenegger PM; Radiation Oncology Unit, Department of Hematology Oncology, Pontifical Catholic University of Chile, Santiago, Chile.
  • Sham JG; Department of Surgery, University of Washington, Seattle, WA, USA.
  • Cavallucci D; Department of Surgery, Royal Brisbane and Women's Hospital, University of Queensland, Brisbane, QLD, Australia.
  • Galvin Z; Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
  • Dawson LA; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
  • Hawkins MA; UCL Cancer Institute, University College London, London, UK; Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
Lancet Gastroenterol Hepatol ; 5(8): 765-775, 2020 08.
Article in English | MEDLINE | ID: covidwho-692971
ABSTRACT
Around the world, recommendations for cancer treatment are being adapted in real time in response to the pandemic of COVID-19. We, as a multidisciplinary team, reviewed the standard management options, according to the Barcelona Clinic Liver Cancer classification system, for hepatocellular carcinoma. We propose treatment recommendations related to COVID-19 for the different stages of hepatocellular carcinoma (ie, 0, A, B, and C), specifically in relation to surgery, locoregional therapies, and systemic therapy. We suggest potential strategies to modify risk during the pandemic and aid multidisciplinary treatment decision making. We also review the multidisciplinary management of intrahepatic cholangiocarcinoma as a potentially curable and incurable diagnosis in the setting of COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Carcinoma, Hepatocellular / Pandemics / Liver Neoplasms Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Lancet Gastroenterol Hepatol Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Carcinoma, Hepatocellular / Pandemics / Liver Neoplasms Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Lancet Gastroenterol Hepatol Year: 2020 Document Type: Article