Histopathological findings in the advanced natural evolution of the SARS-CoV-2 infection.
Rom J Morphol Embryol
; 61(1): 209-218, 2020.
Article
in English
| MEDLINE | ID: covidwho-693877
ABSTRACT
We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the Department of Forensic Medicine from Emergency County Hospital, Drobeta Turnu Severin, Mehedinti County, Romania. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed by reverse transcription polymerase chain reaction (RT-PCR) on the lung tissue which was obtained during autopsy. This case provides the opportunity to study the natural evolution of COVID-19 pneumonia in a young person with clinical signs of pneumonia but without associated comorbidities. The patient had not received any treatment. The histopathological examination of the lung revealed a process of productive proliferation, proteinaceous and fibrin-macrophagic interalveolar spaces exudate, and lesions consistent with vasculitis. In the heart, we identified a cardiac thrombus. These changes are likely to suggest an advanced natural evolution of SARS-CoV-2 virus infection.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Lung
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Rom J Morphol Embryol
Journal subject:
Anatomy
/
Embryology
Year:
2020
Document Type:
Article
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