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COVID-19 associated with extensive pulmonary arterial, intracardiac and peripheral arterial thrombosis.
Ferguson, Katie; Quail, Nathaniel; Kewin, Peter; Blyth, Kevin G.
  • Ferguson K; Department of Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
  • Quail N; Department of Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
  • Kewin P; College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK.
  • Blyth KG; Department of Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
BMJ Case Rep ; 13(8)2020 Aug 03.
Article in English | MEDLINE | ID: covidwho-693991
ABSTRACT
We describe a patient with COVID-19 who developed simultaneous pulmonary, intracardiac and peripheral arterial thrombosis. A 58-year-old man, without major comorbidity, was admitted with a 14-day history of breathlessness. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection was confirmed by laboratory testing. Initial imaging revealed COVID-19 pneumonia but no pulmonary thromboembolism (PTE) on CT pulmonary angiography (CTPA). The patient subsequently developed respiratory failure and left foot ischaemia associated with a rising D-dimer. Repeat CTPA and lower limb CT angiography revealed simultaneous bilateral PTE, biventricular cardiac thrombi and bilateral lower limb arterial occlusions. This case highlights a broad range of vascular sequalae associated with COVID-19 and the fact that these can occur despite a combination of prophylactic and treatment dose anticoagulation.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pulmonary Embolism / Thrombosis / Warfarin / Enoxaparin / Coronavirus Infections / Peripheral Arterial Disease / Pandemics / Heart Diseases Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Language: English Year: 2020 Document Type: Article Affiliation country: Bcr-2020-237460

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pulmonary Embolism / Thrombosis / Warfarin / Enoxaparin / Coronavirus Infections / Peripheral Arterial Disease / Pandemics / Heart Diseases Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Language: English Year: 2020 Document Type: Article Affiliation country: Bcr-2020-237460