An analysis of SARS-CoV-2 cell entry genes identifies the intestine and colorectal cancer as susceptible tissues.

Darvish-Damavandi, Mahnaz; Laycock, James; Ward, Christopher; van Driel, Milou S; Goldgraben, Mae A; Buczacki, Simon Ja

Darvish-Damavandi, Mahnaz; Laycock, James; Ward, Christopher; van Driel, Milou S; Goldgraben, Mae A; Buczacki, Simon Ja.

Darvish-Damavandi M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK.
Laycock J; Cambridge Colorectal Unit, Cambridge University Hospitals NHS Trust, Hills Road, Cambridge, UK.
Ward C; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK.
van Driel MS; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK.
Goldgraben MA; Department of Medical Genetics, University of Cambridge, Addenbrooke's Treatment Centre, Cambridge, UK.
Buczacki SJ; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK.

Br J Surg ; 107(11): e452-e454, 2020 Oct.

Article in English | MEDLINE | ID: covidwho-702766

Subject(s)

Angiotensin-Converting Enzyme 2/metabolism; Colorectal Neoplasms/metabolism; Intestinal Mucosa/metabolism; SARS-CoV-2/physiology; Serine Endopeptidases/metabolism; Virus Internalization; COVID-19/metabolism; Disease Susceptibility; Humans; Receptors, Virus/metabolism; Tissue Donors

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Serine Endopeptidases / Colorectal Neoplasms / Virus Internalization / Angiotensin-Converting Enzyme 2 / SARS-CoV-2 / Intestinal Mucosa Limits: Humans Language: English Journal: Br J Surg Year: 2020 Document Type: Article Affiliation country: Bjs.11911

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