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Preparedness and Reorganization of Care for Coronavirus Disease 2019 Patients in a Swiss ICU: Characteristics and Outcomes of 129 Patients.
Primmaz, Steve; Le Terrier, Christophe; Suh, Noémie; Ventura, François; Boroli, Filippo; Bendjelid, Karim; Cereghetti, Sara; Giraud, Raphaël; Heidegger, Claudia; Pugin, Deborah; Siegenthaler, Nils; Tassaux, Didier; Cabrol, Jean-Clément; Dolet, Nathan; Ellenberger, Christoph; Keli Barcelos, Gleicy; Licker, Marc-Joseph; Savoldelli, Georges; Schiffer, Eduardo; Gayet-Ageron, Angèle; Kaiser, Laurent; Tramèr, Martin R; Pugin, Jérôme.
  • Primmaz S; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Le Terrier C; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Suh N; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Ventura F; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Boroli F; Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Bendjelid K; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Cereghetti S; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Giraud R; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Heidegger C; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Pugin D; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Siegenthaler N; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Tassaux D; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Cabrol JC; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Dolet N; Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Ellenberger C; Department of Research, University Hospital of Caen, Caen, France.
  • Keli Barcelos G; Department of Pediatric Surgery, University Hospital of Caen, Caen, France.
  • Licker MJ; Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Savoldelli G; Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Schiffer E; Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Gayet-Ageron A; Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Kaiser L; Division of Anesthesiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Tramèr MR; Clinical Trial Unit, Division of Clinical Epidemiology, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
  • Pugin J; Division of Infectious Diseases, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.
Crit Care Explor ; 2(8): e0173, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-703523
ABSTRACT

OBJECTIVES:

In many countries, large numbers of critically ill patients with coronavirus disease 2019 are admitted to the ICUs within a short period of time, overwhelming usual care capacities. Preparedness and reorganization ahead of the wave to increase ICU surge capacity may be associated with favorable outcome. The purpose of this study was to report our experience in terms of ICU organization and anticipation, as well as reporting patient characteristics, treatment, and outcomes.

DESIGN:

A prospective observational study.

SETTING:

The division of intensive care at the Geneva University Hospitals (Geneva, Switzerland). PATIENTS All consecutive adult patients with acute respiratory failure due to coronavirus disease 2019 admitted in the ICU between March 9, 2020, and May 19, 2020, were enrolled. Patients' demographic data, comorbidities, laboratory values, treatments, and clinical outcomes were collected.

INTERVENTIONS:

None. MEASUREMENTS AND MAIN

RESULTS:

The ICU was reorganized into cells of six to eight patients under the care of three physicians and five nurses. Its capacity increased from 30 to 110 beds, fully equipped and staffed, transforming the surgical intermediate care unit, the postoperative care facility, and operating theaters into ICUs. Surge capacity has always exceeded the number of patients hospitalized. Among 129 critically ill patients with severe acute hypoxemic respiratory failure, 96% required invasive mechanical ventilation. A total of 105 patients (81%) were discharged alive and 24 died, corresponding to a mortality of 19%. Patients who died were significantly older, with higher severity scores at admission, had higher levels of d-dimers, plasma creatinine, high-sensitive troponin T, C-reactive protein, and procalcitonin, and required more frequent prone sessions.

CONCLUSIONS:

A rapid increase in ICU bed capacity, including adequate equipment and staffing, allowed for a large number of critically ill coronavirus disease 2019 patients to be taken care of within a short period of time. Anticipation and preparedness ahead of the wave may account for the low mortality observed in our center. These results highlight the importance of resources management strategy in the context of the ongoing coronavirus disease 2019 pandemic.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Crit Care Explor Year: 2020 Document Type: Article Affiliation country: CCE.0000000000000173

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Crit Care Explor Year: 2020 Document Type: Article Affiliation country: CCE.0000000000000173