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How the COVID-19 pandemic highlights the necessity of animal research.
Genzel, Lisa; Adan, Roger; Berns, Anton; van den Beucken, Jeroen J J P; Blokland, Arjan; Boddeke, Erik H W G M; Bogers, Willy M; Bontrop, Ronald; Bulthuis, R; Bousema, Teun; Clevers, Hans; Coenen, Tineke C J J; van Dam, Anne-Marie; Deen, Peter M T; van Dijk, K W; Eggen, Bart J L; Elgersma, Ype; Erdogan, Izel; Englitz, Bernhard; Fentener van Vlissingen, J Martje; la Fleur, Susanne; Fouchier, Ron; Fitzsimons, Carlos P; Frieling, Wilbert; Haagmans, Bart; Heesters, Balthasar A; Henckens, Marloes J A G; Herfst, Sander; Hol, Elly; van den Hove, Daniel; de Jonge, Marien I; Jonkers, Jos; Joosten, Leo A B; Kalsbeek, Andries; Kamermans, Maarten; Kampinga, Harm H; Kas, Martien J; Keijer, J Aap; Kersten, Sander; Kiliaan, Amanda J; Kooij, Taco W A; Kooijman, Sander; Koopman, Werner J H; Korosi, Aniko; Krugers, Harm J; Kuiken, Thijs; Kushner, Steven A; Langermans, Jan A M; Lesscher, Heidi M B; Lucassen, Paul J.
  • Genzel L; Radboud University, 6525 XZ Nijmegen, The Netherlands. Electronic address: l.genzel@donders.ru.nl.
  • Adan R; University Medical Center, Utrecht Brain Center, Utrecht University, 3584 CG Utrecht, The Netherlands.
  • Berns A; Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • van den Beucken JJJP; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Blokland A; Maastricht University, 6211 LK Maastricht, The Netherlands.
  • Boddeke EHWGM; University of Groningen, 9712 CP Groningen, The Netherlands; University of Groningen, University Medical Center, 9713 GZ Groningen, The Netherlands.
  • Bogers WM; Biomedical Primate Research Centre, 2288 GJ Rijswijk, The Netherlands.
  • Bontrop R; Biomedical Primate Research Centre, 2288 GJ Rijswijk, The Netherlands.
  • Bulthuis R; Metris BV, 2132 NG Hoofddorp, The Netherlands.
  • Bousema T; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Clevers H; University Medical Center, 3584 CX Utrecht, The Netherlands.
  • Coenen TCJJ; Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • van Dam AM; Amsterdam UMC, location VU University Medical Center, De Boelelaan 1105, 1081 HZ Amsterdam, The Netherlands.
  • Deen PMT; Radboud University, 6525 XZ Nijmegen, The Netherlands.
  • van Dijk KW; Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Eggen BJL; University of Groningen, 9712 CP Groningen, The Netherlands; University of Groningen, University Medical Center, 9713 GZ Groningen, The Netherlands.
  • Elgersma Y; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • Erdogan I; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Englitz B; Radboud University, 6525 XZ Nijmegen, The Netherlands.
  • Fentener van Vlissingen JM; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • la Fleur S; Amsterdam UMC, location VU University Medical Center, De Boelelaan 1105, 1081 HZ Amsterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands.
  • Fouchier R; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • Fitzsimons CP; Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Frieling W; Charles River, 5231 DD Den Bosch, The Netherlands.
  • Haagmans B; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • Heesters BA; Amsterdam UMC, location VU University Medical Center, De Boelelaan 1105, 1081 HZ Amsterdam, The Netherlands.
  • Henckens MJAG; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Herfst S; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • Hol E; University Medical Center, Utrecht Brain Center, Utrecht University, 3584 CG Utrecht, The Netherlands.
  • van den Hove D; Maastricht University, 6211 LK Maastricht, The Netherlands.
  • de Jonge MI; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Jonkers J; Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; Oncode Institute, 3521 AL Utrecht, The Netherlands.
  • Joosten LAB; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Kalsbeek A; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands.
  • Kamermans M; Amsterdam UMC, location VU University Medical Center, De Boelelaan 1105, 1081 HZ Amsterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands.
  • Kampinga HH; University of Groningen, University Medical Center, 9713 GZ Groningen, The Netherlands.
  • Kas MJ; University of Groningen, 9712 CP Groningen, The Netherlands.
  • Keijer JA; Wageningen University, 6700 AH Wageningen, The Netherlands.
  • Kersten S; Wageningen University, 6700 AH Wageningen, The Netherlands.
  • Kiliaan AJ; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Kooij TWA; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Kooijman S; Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Koopman WJH; Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Korosi A; Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Krugers HJ; Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Kuiken T; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • Kushner SA; Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
  • Langermans JAM; Biomedical Primate Research Centre, 2288 GJ Rijswijk, The Netherlands; Utrecht University, 3584 CS Utrecht, The Netherlands.
  • Lesscher HMB; Utrecht University, 3584 CS Utrecht, The Netherlands.
  • Lucassen PJ; Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
Curr Biol ; 30(18): R1014-R1018, 2020 09 21.
Article in English | MEDLINE | ID: covidwho-703973
ABSTRACT
Recently, a petition was offered to the European Commission calling for an immediate ban on animal testing. Although a Europe-wide moratorium on the use of animals in science is not yet possible, there has been a push by the non-scientific community and politicians for a rapid transition to animal-free innovations. Although there are benefits for both animal welfare and researchers, advances on alternative methods have not progressed enough to be able to replace animal research in the foreseeable future. This trend has led first and foremost to a substantial increase in the administrative burden and hurdles required to make timely advances in research and treatments for human and animal diseases. The current COVID-19 pandemic clearly highlights how much we actually rely on animal research. COVID-19 affects several organs and systems, and the various animal-free alternatives currently available do not come close to this complexity. In this Essay, we therefore argue that the use of animals is essential for the advancement of human and veterinary health.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Animal Experimentation / Biomedical Research / Disease Models, Animal / Pandemics Type of study: Qualitative research Limits: Animals / Humans Language: English Journal: Curr Biol Journal subject: Biology Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Animal Experimentation / Biomedical Research / Disease Models, Animal / Pandemics Type of study: Qualitative research Limits: Animals / Humans Language: English Journal: Curr Biol Journal subject: Biology Year: 2020 Document Type: Article