Bone biology and COVID-19 infection: Is ACE2 a potential influence factor?
Med Hypotheses
; 144: 110178, 2020 Nov.
Article
in English
| MEDLINE | ID: covidwho-704009
ABSTRACT
The outbreak of coronavirus disease 2019 (COVID-19) has posed a severe threat to global health management system since it has been detected in the human body. This pandemic was prompted by severe acute respiratory syndrome coronaviruses 2 (SARS-CoV-2) and rapidly developed into a public emergency with an alarming increase in cases and deaths. The increasing explorations to SARS-CoV-2 infection guide us to consider whether bone lesion is followed by this pathologic process. We especially focus on the underlying pathobiology that SARS-CoV-2 possibly mediated in bone remodeling and analyze the association of bone destruction with ACE2 in COVID-19 incidence, for preferable understanding the pathogenesis and providing necessary clinical management in orthopedics.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Bone and Bones
/
Bone Diseases
/
Angiotensin-Converting Enzyme 2
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Animals
/
Humans
Language:
English
Journal:
Med Hypotheses
Year:
2020
Document Type:
Article
Affiliation country:
J.mehy.2020.110178
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