Genetic comparison among various coronavirus strains for the identification of potential vaccine targets of SARS-CoV2.
Infect Genet Evol
; 89: 104490, 2021 04.
Article
in English
| MEDLINE | ID: covidwho-705778
ABSTRACT
On-going pandemic pneumonia outbreak COVID-19 has raised an urgent public health issue worldwide impacting millions of people with a continuous increase in both morbidity and mortality. The causative agent of this disease is identified and named as SARS-CoV2 because of its genetic relatedness to SARS-CoV species that was responsible for the 2003 coronavirus outbreak. The immense spread of the disease in a very small period demands urgent development of therapeutic and prophylactic interventions for the treatment of SARS-CoV2 infected patients. A plethora of research is being conducted globally on this novel coronavirus strain to gain knowledge about its origin, evolutionary history, and phylogeny. This review is an effort to compare genetic similarities and diversifications among coronavirus strains, which can hint towards the susceptible antigen targets of SARS-CoV2 to come up with the potential therapeutic and prophylactic interventions for the prevention of this public threat.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Genes, Viral
/
COVID-19 Vaccines
/
SARS-CoV-2
Type of study:
Prognostic study
Topics:
Vaccines
Language:
English
Journal:
Infect Genet Evol
Journal subject:
Biology
/
Communicable Diseases
/
Genetics
Year:
2021
Document Type:
Article
Affiliation country:
J.meegid.2020.104490
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