Status quo and review of clinical application of antibody detection for 2019-nCoV

ABSTRACT

With the gradual progress of epidemic prevention and control work, the process of epidemic prevention and control in COVID-19 has entered a critical period. As the main method to diagnose patients with COVID-19,the disadvantages of nucleic acid detection are gradually revealed. As an important immune response product, specific antibodies have been rapidly applied to the laboratory detection of 2019 novel coronavirus (2019-nCoV), combined with nucleic acid detection for rapid diagnosis and screening of patients with COVID-19. This paper explores and discusses the production pattern and common detection methods of 2019-nCoV specific antibodies and the application and limitations of antibody detection in the clinical work to promote the application and development of specific antibody in COVID-19 diagnosis.