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How should diagnostic kits development adapt quickly in COVID 19-like pandemic models? Pros and cons of sensory platforms used in COVID-19 sensing.
Moulahoum, Hichem; Ghorbanizamani, Faezeh; Zihnioglu, Figen; Turhan, Kutsal; Timur, Suna.
  • Moulahoum H; Biochemistry Department, Faculty of Sciences, Ege University, 35100, Bornova, Izmir, Turkey. Electronic address: Hic_moul@hotmail.com.
  • Ghorbanizamani F; Biochemistry Department, Faculty of Sciences, Ege University, 35100, Bornova, Izmir, Turkey.
  • Zihnioglu F; Biochemistry Department, Faculty of Sciences, Ege University, 35100, Bornova, Izmir, Turkey.
  • Turhan K; Department of Thoracic Surgery, Faculty of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Timur S; Biochemistry Department, Faculty of Sciences, Ege University, 35100, Bornova, Izmir, Turkey; Central Research Test and Analysis Laboratory Application and Research Center, Ege University, 35100, Bornova, Izmir, Turkey. Electronic address: suna.timur@ege.edu.tr.
Talanta ; 222: 121534, 2021 Jan 15.
Article in English | MEDLINE | ID: covidwho-709442
ABSTRACT
As COVID-19 has reached pandemic status and the number of cases continues to grow, widespread availability of diagnostic testing is critical in helping identify and control the emergence of this rapidly spreading and serious illness. However, a lacking in making a quick reaction to the threat and starting early development of diagnostic sensing tools has had an important impact globally. In this regard, here we will review critically the current developed diagnostic tools in response to the COVID-19 pandemic and compare the different types through the discussion of their pros and cons such as nucleic acid detection tests (including PCR and CRISPR), antibody and protein-based diagnosis tests. In addition, potential technologies that are under development such as on-site diagnosis platforms, lateral flow, and portable PCR units are discussed. Data collection and epidemiological analysis could also be an interesting factor to incorporate with the emerging technologies especially with the wide access to smartphones. Lastly, a SWOT analysis and perspectives on how the development of novel sensory platforms should be treated by the different decision-makers are analyzed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Clinical Laboratory Techniques / Pandemics Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Language: English Journal: Talanta Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Clinical Laboratory Techniques / Pandemics Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Language: English Journal: Talanta Year: 2021 Document Type: Article