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Serological survey of SARS-CoV-2 for experimental, domestic, companion and wild animals excludes intermediate hosts of 35 different species of animals.
Deng, Junhua; Jin, Yipeng; Liu, Yuxiu; Sun, Jie; Hao, Liying; Bai, Jingjing; Huang, Tian; Lin, Degui; Jin, Yaping; Tian, Kegong.
  • Deng J; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
  • Jin Y; College of Veterinary Medicine, China Agricultural University, Beijing, China.
  • Liu Y; National Research Center for Veterinary Medicine, Luoyang, China.
  • Sun J; National Research Center for Veterinary Medicine, Luoyang, China.
  • Hao L; National Research Center for Veterinary Medicine, Luoyang, China.
  • Bai J; National Research Center for Veterinary Medicine, Luoyang, China.
  • Huang T; National Research Center for Veterinary Medicine, Luoyang, China.
  • Lin D; College of Veterinary Medicine, China Agricultural University, Beijing, China.
  • Jin Y; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
  • Tian K; National Research Center for Veterinary Medicine, Luoyang, China.
Transbound Emerg Dis ; 67(4): 1745-1749, 2020 Jul.
Article in English | MEDLINE | ID: covidwho-71843
Semantic information from SemMedBD (by NLM)
1. Study USES Detection
Subject
Study
Predicate
USES
Object
Detection
2. 2019 novel coronavirus PROCESS_OF Patients
Subject
2019 novel coronavirus
Predicate
PROCESS_OF
Object
Patients
3. Study USES Detection
Subject
Study
Predicate
USES
Object
Detection
4. 2019 novel coronavirus PROCESS_OF Patients
Subject
2019 novel coronavirus
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
The pandemic SARS-CoV-2 has been reported in 123 countries with more than 5,000 patients died from it. However, the original and intermediate hosts of the virus remain unknown. In this study, 1,914 serum samples from 35 animal species were used for detection of SARS-CoV-2-specific antibodies using double-antigen sandwich ELISA after validating its specificity and sensitivity. The results showed that no SARS-CoV-2-specific antibodies were detected in above samples which excluded the possibility of 35 animal species as intermediate host for SARS-CoV-2. More importantly, companion animals including pet dogs (including one dog the SARS-CoV-2 patient kept and two dogs which had close contact with it) and cats, street dogs and cats also showed serological negative to SARS-CoV-2, which relieved the public concerns for the pets as SARS-CoV-2 carriers.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Clinical Laboratory Techniques / Pandemics Type of study: Diagnostic study Limits: Animals Language: English Journal: Transbound Emerg Dis Journal subject: Veterinary Medicine Year: 2020 Document Type: Article Affiliation country: Tbed.13577

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Clinical Laboratory Techniques / Pandemics Type of study: Diagnostic study Limits: Animals Language: English Journal: Transbound Emerg Dis Journal subject: Veterinary Medicine Year: 2020 Document Type: Article Affiliation country: Tbed.13577