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Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes.
Robinson, Emma L; Alkass, Kanar; Bergmann, Olaf; Maguire, Janet J; Roderick, H Llewelyn; Davenport, Anthony P.
  • Robinson EL; Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM) Maastricht University, The Netherlands and Laboratory of Experimental Cardiology, Dept. of Cardiovascular Sciences, KU Leuven, Campus Gasthuisberg, Herestraat 49, Leuven B-3000, Belgium.
  • Alkass K; Karolinska Institutet, BioClinicum, Oncology and Pathology, The National Board of Forensic Medicine, SE-17177 Stockholm, Stockholm, Sweden.
  • Bergmann O; Center for Regenerative Therapies Dresden, TU-Dresden, Fetscherstrasse 105, Dresden 01307, Germany.; Karolinska Institutet, Biomedicum, Cell and Molecular Biology, SE-17177, Stockholm, Sweden.
  • Maguire JJ; Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
  • Roderick HL; KU Leuven, Department of Cardiovascular Sciences, Laboratory of Experimental Cardiology, Belgium and K.G. Jebsen Center for Cardiac Research, University of Oslo, 3000 Leuven, Oslo, Norway.
  • Davenport AP; Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. Electronic address: apd10@medschl.cam.ac.uk.
J Mol Cell Cardiol ; 147: 88-91, 2020 10.
Article in English | MEDLINE | ID: covidwho-719044
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Serine Endopeptidases / Coronavirus Infections / Peptidyl-Dipeptidase A / Virus Attachment / Virus Internalization Limits: Humans Language: English Journal: J Mol Cell Cardiol Year: 2020 Document Type: Article Affiliation country: J.yjmcc.2020.08.009

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Serine Endopeptidases / Coronavirus Infections / Peptidyl-Dipeptidase A / Virus Attachment / Virus Internalization Limits: Humans Language: English Journal: J Mol Cell Cardiol Year: 2020 Document Type: Article Affiliation country: J.yjmcc.2020.08.009