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Low risk of serological cross-reactivity between dengue and COVID-19.
Spinicci, Michele; Bartoloni, Alessandro; Mantella, Antonia; Zammarchi, Lorenzo; Rossolini, Gian Maria; Antonelli, Alberto.
  • Spinicci M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Bartoloni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Mantella A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Zammarchi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Antonelli A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Mem Inst Oswaldo Cruz ; 115: e200225, 2020.
Article in English | MEDLINE | ID: covidwho-723314
ABSTRACT
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Cross Reactions / Dengue / Antibodies, Viral Type of study: Diagnostic study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Mem Inst Oswaldo Cruz Year: 2020 Document Type: Article Affiliation country: 0074-02760200225

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Cross Reactions / Dengue / Antibodies, Viral Type of study: Diagnostic study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Mem Inst Oswaldo Cruz Year: 2020 Document Type: Article Affiliation country: 0074-02760200225