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25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor.
Zu, Shulong; Deng, Yong-Qiang; Zhou, Chao; Li, Jie; Li, Lili; Chen, Qi; Li, Xiao-Feng; Zhao, Hui; Gold, Sarah; He, Jun; Li, Xiang; Zhang, Changqing; Yang, Heng; Cheng, Genhong; Qin, Cheng-Feng.
  • Zu S; Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.
  • Deng YQ; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, 215123, China.
  • Zhou C; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
  • Li J; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
  • Li L; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
  • Chen Q; Department of Laboratory Medicine, TaiHe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, China.
  • Li XF; Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.
  • Zhao H; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, 215123, China.
  • Gold S; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
  • He J; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
  • Li X; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
  • Zhang C; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Yang H; Institute of Laboratory Animal Sciences, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, 100050, China.
  • Cheng G; Porton (Shanghai) R&D Center, Shanghai, 200241, China.
  • Qin CF; CoSci Med-Tech Co., Ltd, Beijing, 100083, China.
Cell Res ; 30(11): 1043-1045, 2020 11.
Article in English | MEDLINE | ID: covidwho-723586
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Hydroxycholesterols Type of study: Case report / Diagnostic study / Prognostic study Limits: Aged / Animals / Female / Humans Language: English Journal: Cell Res Year: 2020 Document Type: Article Affiliation country: S41422-020-00398-1

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Hydroxycholesterols Type of study: Case report / Diagnostic study / Prognostic study Limits: Aged / Animals / Female / Humans Language: English Journal: Cell Res Year: 2020 Document Type: Article Affiliation country: S41422-020-00398-1