A novel role for lidocaine in COVID-19 patients?

Finnerty, Dylan T; Buggy, Donal J

Finnerty, Dylan T; Buggy, Donal J.

Finnerty DT; Division of Anaesthesiology, Mater Misericordiae University Hospital, Dublin, Ireland; School of Medicine, University College Dublin, Dublin, Ireland; EU COST Action 15204, Euro-Periscope, Dublin, Ireland. Electronic address: dylantfinnerty@gmail.com.
Buggy DJ; Division of Anaesthesiology, Mater Misericordiae University Hospital, Dublin, Ireland; School of Medicine, University College Dublin, Dublin, Ireland; EU COST Action 15204, Euro-Periscope, Dublin, Ireland; Outcomes Research, Cleveland Clinic, Cleveland, OH, USA.

Br J Anaesth ; 125(4): e391-e394, 2020 10.

Article in English | MEDLINE | ID: covidwho-724431

Subject(s)

Anesthetics, Local/pharmacology; Anesthetics, Local/therapeutic use; Coronavirus Infections/drug therapy; Extracellular Traps/virology; Lidocaine/pharmacology; Lidocaine/therapeutic use; Pneumonia, Viral/drug therapy; COVID-19; Coronavirus Infections/metabolism; Cytokines/metabolism; Extracellular Traps/drug effects; Humans; Neutrophils/virology; Pandemics; Pneumonia, Viral/metabolism; Respiratory Distress Syndrome/complications; Respiratory Distress Syndrome/virology; Thrombosis

Keywords

COVID-19; NETs; cytokine storm; lidocaine; netosis; neutrophil; thrombosis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Extracellular Traps / Anesthetics, Local / Lidocaine Topics: Long Covid Limits: Humans Language: English Journal: Br J Anaesth Year: 2020 Document Type: Article

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