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[What we learned from SARS may provide important insights into understanding and management of coronavirus disease 2019].
Liu, Y J; Yang, Y L; Xu, Y.
  • Liu YJ; Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Yang YL; Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Xu Y; Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Zhonghua Jie He He Hu Xi Za Zhi ; 43(4): 339-344, 2020 Apr 12.
Article in Chinese | MEDLINE | ID: covidwho-72745
Semantic information from SemMedBD (by NLM)
1. Clinical Deterioration ASSOCIATED_WITH Severe Acute Respiratory Syndrome
Subject
Clinical Deterioration
Predicate
ASSOCIATED_WITH
Object
Severe Acute Respiratory Syndrome
2. Clinical Deterioration ASSOCIATED_WITH COVID-19
Subject
Clinical Deterioration
Predicate
ASSOCIATED_WITH
Object
COVID-19
3. Clinical Deterioration ASSOCIATED_WITH Severe Acute Respiratory Syndrome
Subject
Clinical Deterioration
Predicate
ASSOCIATED_WITH
Object
Severe Acute Respiratory Syndrome
4. Clinical Deterioration ASSOCIATED_WITH COVID-19
Subject
Clinical Deterioration
Predicate
ASSOCIATED_WITH
Object
COVID-19
ABSTRACT
The rapid spread of the coronavirus disease 2019 (COVID-19) has become a global threat. But the pathogenesis and treatment of the disease are not clear yet. Virological researches revealed close relationship between 2019-nCoV and SARS-CoV. The experience and knowledge we gained from severe acute respiratory syndrome (SARS), especially with regard to the time course of viral replication, host immune response and clinical progression of the patient, may provide important insights into understanding and management of COVID-19. Clinical deterioration accompanied by decreasing viral load in the second week after symptom onset was noted both in SARS and COVID-19, suggesting that the lung damage at this phase is more related to excessive host immune response rather than uncontrolled viral replication.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Severe Acute Respiratory Syndrome / SARS Virus Limits: Humans Language: Chinese Journal: Zhonghua Jie He He Hu Xi Za Zhi Year: 2020 Document Type: Article Affiliation country: Cma.j.cn112147-20200218-00119

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Severe Acute Respiratory Syndrome / SARS Virus Limits: Humans Language: Chinese Journal: Zhonghua Jie He He Hu Xi Za Zhi Year: 2020 Document Type: Article Affiliation country: Cma.j.cn112147-20200218-00119