Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection.

Capone, Christine A; Subramony, Anupama; Sweberg, Todd; Schneider, James; Shah, Sareen; Rubin, Lorry; Schleien, Charles; Epstein, Shilpi; Johnson, Jennifer C; Kessel, Aaron; Misra, Nila; Mitchell, Elizabeth; Palumbo, Nancy; Rajan, Sujatha; Rocker, Josh; Williamson, Kristy; Davidson, Karina W

Capone, Christine A; Subramony, Anupama; Sweberg, Todd; Schneider, James; Shah, Sareen; Rubin, Lorry; Schleien, Charles; Epstein, Shilpi; Johnson, Jennifer C; Kessel, Aaron; Misra, Nila; Mitchell, Elizabeth; Palumbo, Nancy; Rajan, Sujatha; Rocker, Josh; Williamson, Kristy; Davidson, Karina W.

Capone CA; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Subramony A; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Sweberg T; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Schneider J; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Shah S; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Rubin L; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Schleien C; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY. Electronic address: cschleien@northwell.edu.
Epstein S; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Johnson JC; Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY.
Kessel A; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Misra N; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Mitchell E; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Palumbo N; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Rajan S; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Rocker J; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Williamson K; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.
Davidson KW; Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY.

J Pediatr ; 224: 141-145, 2020 09.

Article in English | MEDLINE | ID: covidwho-727666

ABSTRACT

ABSTRACT

We report on the presentation and course of 33 children with multisystem inflammatory syndrome in children and confirmed severe acute respiratory syndrome coronavirus 2 infection. Hemodynamic instability and cardiac dysfunction were prominent findings, with most patients exhibiting rapid resolution following anti-inflammatory therapy.

Subject(s)

Coronavirus Infections/complications; Pneumonia, Viral/complications; Systemic Inflammatory Response Syndrome/diagnosis; Systemic Inflammatory Response Syndrome/therapy; Adolescent; Anti-Inflammatory Agents/therapeutic use; Betacoronavirus; COVID-19; Child; Child, Preschool; Coronary Aneurysm; Coronavirus Infections/drug therapy; Female; Fever; Humans; Inflammation; Male; Mucocutaneous Lymph Node Syndrome/diagnosis; New York City; Pandemics; Retrospective Studies; SARS-CoV-2; Shock/complications; Treatment Outcome; Ventricular Dysfunction, Left/complications; COVID-19 Drug Treatment

Keywords

adolescents; coronary aneurysm; inflammation; kawasaki disease

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Systemic Inflammatory Response Syndrome Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Country/Region as subject: North America Language: English Journal: J Pediatr Year: 2020 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google