Can charcoal improve outcomes in COVID-19 infections?

Khitan, Zeid J; Khawaja, Imran; Mufson, Maurice A; Sanabria, Juan R; Abraham, Nader G; Peterson, Stephen J; Sundaram, Uma; Shapiro, Joseph I

Khitan, Zeid J; Khawaja, Imran; Mufson, Maurice A; Sanabria, Juan R; Abraham, Nader G; Peterson, Stephen J; Sundaram, Uma; Shapiro, Joseph I.

Khitan ZJ; Joan C. Edwards School of Medicine, Marshall University, United States.
Khawaja I; Joan C. Edwards School of Medicine, Marshall University, United States.
Mufson MA; Joan C. Edwards School of Medicine, Marshall University, United States.
Sanabria JR; Joan C. Edwards School of Medicine, Marshall University, United States.
Abraham NG; New York Medical College, Touro University, United States.
Peterson SJ; New York Presbyterian Brooklyn Methodist Hospital/Weill Cornell Medicine, United States.
Sundaram U; Joan C. Edwards School of Medicine, Marshall University, United States.
Shapiro JI; Joan C. Edwards School of Medicine, Marshall University, United States. Electronic address: shapiroj@marshall.edu.

Med Hypotheses ; 144: 110176, 2020 Nov.

Article in English | MEDLINE | ID: covidwho-728773

ABSTRACT

ABSTRACT

COVID-19 infection causes considerable morbidity and mortality, especially to those who are aged, have impaired renal function and are obese. We propose to examine the potential utility of oral activated charcoal with the hypothesis that such treatment would lower absorption of microbiome derived toxins and ameliorate systemic oxidant stress and inflammation.

Subject(s)

COVID-19/therapy; Charcoal/pharmacology; Gastrointestinal Microbiome; Kidney Diseases/complications; Obesity/complications; Adipocytes/cytology; Adipocytes/metabolism; Antiviral Agents/therapeutic use; COVID-19/microbiology; Cytokines/metabolism; Humans; Inflammation; Models, Theoretical; Oxidants/metabolism; Oxidative Stress; Risk

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Charcoal / Gastrointestinal Microbiome / COVID-19 / Kidney Diseases / Obesity Type of study: Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article Affiliation country: J.mehy.2020.110176

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