Thoughts on detecting tissue distribution of potential COVID-19 receptors
Future Virology
; 2020.
Article
| WHO COVID | ID: covidwho-732935
ABSTRACT
Aim:
As a novel coronavirus, coronavirus disease 2019 (COVID-19) has caused a global epidemic. Many clinical data show that COVID-19 can not only cause viral pneumonia but also damage a variety of target organs.Materials &methods:
We searched some open online datasets, such as Gene ORGANizer, the Human Protein Atlas and Pubmed, to explore the tissue distribution of potential COVID-19 receptors (ACE2, CD209, CLEC4M and BSG) in the human body.Results:
The above potential COVID-19 receptors were highly expressed in the lungs, intestine, kidney, liver, heart, testis, placenta, hematopoietic tissue and nerve tissue.Conclusion:
It is speculated that they may be potentially high-risk organs susceptible to COVID-19 infection. It is expectant to provide some help for further research in the future.
Full text:
Available
Collection:
Databases of international organizations
Database:
WHO COVID
Type of study:
Prognostic study
/
Reviews
Journal:
Future Virology
Year:
2020
Document Type:
Article
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