Functional respiratory imaging identifies redistribution of pulmonary blood flow in patients with COVID-19.
Thorax
; 76(2): 182-184, 2021 02.
Article
in English
| MEDLINE | ID: covidwho-733132
ABSTRACT
An increasing observation is that some patients with COVID-19 have normal lung compliance but significant hypoxaemia different from typical acute respiratory distress syndrome (ARDS). We hypothesised that changes in pulmonary blood distribution may be partially responsible and used functional respiratory imaging on CT scans to calculate pulmonary blood volume. We found that patients with COVID-19 had significantly reduced blood volume in the smaller calibre blood vessels (here defined as <5 mm2 cross-sectional area) compared with matched ARDS patients and healthy controls. This suggests that using high levels of PEEP may not alone be enough to oxygenate these patients and that additional management strategies may be needed.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiratory Mechanics
/
Lung Compliance
/
Pulmonary Circulation
/
SARS-CoV-2
/
COVID-19
/
Lung
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Language:
English
Journal:
Thorax
Year:
2021
Document Type:
Article
Affiliation country:
Thoraxjnl-2020-215395
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