Co-infection of SARS-CoV-2 and <i>Bordetella bronchiseptica</i> in a young man with idiopathic non-cystic bronchiectasis and vitamin D<sub>3</sub> deficiency.

Faqihi, Fahad; Alharthy, Abdulrahman; Pirompanich, Pattarin; Noor, Alfateh; Shahzad, Ahmad; Nasim, Nasir; Balhamar, Abdullah; Memish, Ziad A; Karakitsos, Dimitrios

Co-infection of SARS-CoV-2 and Bordetella bronchiseptica in a young man with idiopathic non-cystic bronchiectasis and vitamin D₃ deficiency.

Faqihi, Fahad; Alharthy, Abdulrahman; Pirompanich, Pattarin; Noor, Alfateh; Shahzad, Ahmad; Nasim, Nasir; Balhamar, Abdullah; Memish, Ziad A; Karakitsos, Dimitrios.

Faqihi F; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Alharthy A; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Pirompanich P; Division of Pulmonary and Critical Care Medicine Department of Medicine, Thammasat University, Pathumthani, Thailand.
Noor A; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Shahzad A; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Nasim N; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Balhamar A; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Memish ZA; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Karakitsos D; Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.

Respir Med Case Rep ; 31: 101203, 2020.

Article in English | MEDLINE | ID: covidwho-733634

ABSTRACT

ABSTRACT

This is the first reported case, to our knowledge, of co-infection of Bordetella bronchiseptica and SARS-CoV-2 in a young patient with underlying idiopathic bronchiectasis and vitamin D3 deficiency that was treated successfully with a combination therapeutic regime integrating doxycycline, empiric therapies for COVID-19, vitamin D supplementation, and supportive ICU care. Large prospective studies are required to investigate further the role of co-infections in COVID-19 patients with bronchiectasis. Randomized control trials should examine the putative beneficial role of vitamin D supplementation in patients with COVID-19.

Keywords

Acute respiratory distress syndrome; Bordetella bronchiseptica; COVID-19; CT, computed tomography; ED, emergency department; HFNC, high flow nasal cannula; ICU, intensive care unit; Idiopathic non-cystic bronchiectasis; MV, mechanical ventilation; RT-PCR, Real-Time-Polymerase-Chain-Reaction; SARS-CoV-2 disease, COVID-19; SpO2/FiO2, partial arterial pressure of oxygen to fractional inspired concentration of oxygen; Vitamin D supplementation

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Respir Med Case Rep Year: 2020 Document Type: Article Affiliation country: J.rmcr.2020.101203

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