Your browser doesn't support javascript.
MERS-CoV infection among healthcare workers and risk factors for death: Retrospective analysis of all laboratory-confirmed cases reported to WHO from 2012 to 2 June 2018.
Elkholy, Amgad A; Grant, Rebecca; Assiri, Abdullah; Elhakim, Mohamed; Malik, Mamunur R; Van Kerkhove, Maria D.
  • Elkholy AA; Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
  • Grant R; Centre for Global Health, Institut Pasteur, Paris, France; Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland.
  • Assiri A; Ministry of Health, Riyadh, Saudi Arabia.
  • Elhakim M; Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
  • Malik MR; Infectious Hazard Management Unit, Department of Health Emergencies, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
  • Van Kerkhove MD; Department of Infectious Hazard Management, WHO Health Emergencies Programme, World Health Organization, Geneva, Switzerland. Electronic address: vankerkhovem@who.int.
J Infect Public Health ; 13(3): 418-422, 2020 Mar.
Article in English | MEDLINE | ID: covidwho-7352
ABSTRACT

BACKGROUND:

Approximately half of the reported laboratory-confirmed infections of Middle East respiratory syndrome coronavirus (MERS-CoV) have occurred in healthcare settings, and healthcare workers constitute over one third of all secondary infections. This study aimed to describe secondary cases of MERS-CoV infection among healthcare workers and to identify risk factors for death.

METHODS:

A retrospective analysis was conducted on epidemiological data of laboratory-confirmed MERS-CoV cases reported to the World Health Organization from September 2012 to 2 June 2018. We compared all secondary cases among healthcare workers with secondary cases among non-healthcare workers. Multivariable logistic regression identified risk factors for death.

RESULTS:

Of the 2223 laboratory-confirmed MERS-CoV cases reported to WHO, 415 were healthcare workers and 1783 were non-healthcare workers. Compared with non-healthcare workers cases, healthcare workers cases were younger (P < 0.001), more likely to be female (P < 0.001), non-nationals (P < 0.001) and asymptomatic (P < 0.001), and have fewer comorbidities (P < 0.001) and higher rates of survival (P < 0.001). Year of infection (2013-2018) and having no comorbidities were independent protective factors against death among secondary healthcare workers cases.

CONCLUSION:

Being able to protect healthcare workers from high threat respiratory pathogens, such as MERS-CoV is important for being able to reduce secondary transmission of MERS-CoV in healthcare-associated outbreaks. By extension, reducing infection in healthcare workers improves continuity of care for all patients within healthcare facilities.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Health Personnel / Coronavirus Infections / Middle East Respiratory Syndrome Coronavirus Type of study: Etiology study / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: J Infect Public Health Journal subject: Communicable Diseases / Public Health Year: 2020 Document Type: Article Affiliation country: J.jiph.2019.04.011

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Health Personnel / Coronavirus Infections / Middle East Respiratory Syndrome Coronavirus Type of study: Etiology study / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: J Infect Public Health Journal subject: Communicable Diseases / Public Health Year: 2020 Document Type: Article Affiliation country: J.jiph.2019.04.011