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The role of neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio in the prognosis of type 2 diabetics with COVID-19.
Liu, Gaoli; Zhang, Shaowen; Hu, Haifeng; Liu, TingTing; Huang, Jie.
  • Liu G; Attending Physician, Department of Thoracic surgery, Renmin Hospital of Wuhan University, PR China.
  • Zhang S; Attending Physician, Department of Thoracic surgery, Renmin Hospital of Wuhan University, PR China.
  • Hu H; Attending Physician, Department of Thoracic surgery, Renmin Hospital of Wuhan University, PR China.
  • Liu T; Attending Physician, Department of Cardiac Function, Renmin Hospital of Wuhan University, PR China.
  • Huang J; Chief Physician, Department of Thoracic surgery, Renmin Hospital of Wuhan University, PR China.
Scott Med J ; 65(4): 154-160, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-736303
ABSTRACT

OBJECTIVES:

To assess the prognostic value of neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio and red cell distribution width in type 2 diabetics with COVID-19.

METHODS:

We collected the data of type 2 diabetics with COVID-19 treated in our hospital from January 28 to March 15, 2020 and performed a retrospective analysis. Using severity, duration of hospital stay, and the time required for nucleic acid results became negative as prognostic indicators, we explored the relationship between these inflammation-based markers and prognosis of type 2 diabetics with COVID-19.

RESULTS:

A total of 134 type 2 diabetics with COVID-19 were selected for this study. Correlation analysis showed that NLR, LMR and RDW were correlated with prognosis (P < 0.05). In multivariate regression analysis after controlling for the relevant confounding factors, COVID-19 diabetes patients with higher NLR had heavier severity, longer duration of hospital stay, more time required for nucleic acid results became negative, and heavier hospital expenses (P < 0.05). ROC curve result displayed that higher NLR predicted all prognostic indicators with statistical significance, and lower LMR predicted severe and extremely severe with statistical significance (P < 0.05).

CONCLUSIONS:

NLR is a more powerful and practical marker for predicting the prognosis of type 2 diabetic COVID-19 patients that is simple and fast.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Lymphocyte Count / Diabetes Mellitus, Type 2 / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Scott Med J Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Lymphocyte Count / Diabetes Mellitus, Type 2 / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Scott Med J Year: 2020 Document Type: Article