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Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion.
Kusaba, Yusaku; Izumi, Shinyu; Takasaki, Jin; Suzuki, Manabu; Katagiri, Daisuke; Katsuno, Takashi; Matsumoto, Shuichiro; Sakamoto, Keita; Hashimoto, Masao; Ohmagari, Norio; Katano, Harutaka; Suzuki, Tadaki; Hojo, Masayuki; Sugiyama, Haruhito.
  • Kusaba Y; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Izumi S; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Takasaki J; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Suzuki M; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Katagiri D; Department of Nephrology, National Center for Global Health and Medicine, Japan.
  • Katsuno T; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Matsumoto S; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Sakamoto K; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Hashimoto M; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Ohmagari N; Diseases Control and Prevention Center, National Center for Global Health and Medicine, Japan.
  • Katano H; Department of Pathology, National Institute of Infectious Diseases, Japan.
  • Suzuki T; Department of Pathology, National Institute of Infectious Diseases, Japan.
  • Hojo M; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
  • Sugiyama H; Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Intern Med ; 59(19): 2405-2408, 2020 Oct 01.
Article in English | MEDLINE | ID: covidwho-736583
ABSTRACT
An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Polymyxin B / Respiratory Insufficiency / Hemoperfusion / Coronavirus Infections / Betacoronavirus Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Humans / Male Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2020 Document Type: Article Affiliation country: Internalmedicine.5413-20

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Polymyxin B / Respiratory Insufficiency / Hemoperfusion / Coronavirus Infections / Betacoronavirus Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Humans / Male Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2020 Document Type: Article Affiliation country: Internalmedicine.5413-20