Absence of SARS-CoV-2 in the effluent of peritoneal dialysis patients.
Perit Dial Int
; 40(5): 499-503, 2020 09.
Article
in English
| MEDLINE | ID: covidwho-737735
ABSTRACT
The pandemic of respiratory disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is life-threatening in peritoneal dialysis (PD) patients. In PD patients with systemic viral infections, peritoneal effluent may be theoretically contaminated. We searched for the presence of SARS-CoV-2 genetic material by real-time reverse transcriptase-polymerase chain reaction assays in serial PD effluents of three PD infected patients. Nasopharyngeal swabs obtained at admission showed high viral load in all three patients, whereas none of the PD effluent specimen tested positive, even after dialysate concentration. Those results support at most a very low SARS-CoV-2 dissemination risk by the peritoneal effluent of PD patients. Imposing special disposal procedures, such as the instillation of hypochlorite in the drainage bags to prevent viral spread to health-care workers, are probably not required.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Ascitic Fluid
/
Peritoneal Dialysis
/
Coronavirus Infections
/
Severe Acute Respiratory Syndrome
/
Kidney Failure, Chronic
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Perit Dial Int
Journal subject:
Nephrology
Year:
2020
Document Type:
Article
Affiliation country:
0896860820953061
Similar
MEDLINE
...
LILACS
LIS