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Children account for a small proportion of diagnoses of SARS-CoV-2 infection and do not exhibit greater viral loads than adults.
Colson, Philippe; Tissot-Dupont, Hervé; Morand, Aurélie; Boschi, Céline; Ninove, Laetitia; Esteves-Vieira, Vera; Gautret, Philippe; Brouqui, Philippe; Parola, Philippe; Lagier, Jean-Christophe; Zandotti, Christine; Million, Matthieu; La Scola, Bernard; Raoult, Didier.
  • Colson P; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Tissot-Dupont H; Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille University, 27 boulevard Jean Moulin, 13005, Marseille, France.
  • Morand A; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Boschi C; Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille University, 27 boulevard Jean Moulin, 13005, Marseille, France.
  • Ninove L; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Esteves-Vieira V; Pédiatrie spécialisée et médecine infantile, AP-HM, Hôpital de la Timone, Marseille, France.
  • Gautret P; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Brouqui P; Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille University, 27 boulevard Jean Moulin, 13005, Marseille, France.
  • Parola P; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Lagier JC; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Zandotti C; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Million M; Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille University, 27 boulevard Jean Moulin, 13005, Marseille, France.
  • La Scola B; IHU Méditerranée Infection, 19-21 boulevard Jean Moulin, 13005, Marseille, France.
  • Raoult D; Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), Microbes Evolution Phylogeny and Infections (MEPHI), Aix-Marseille University, 27 boulevard Jean Moulin, 13005, Marseille, France.
Eur J Clin Microbiol Infect Dis ; 39(10): 1983-1987, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-737821
ABSTRACT
Previous reports have suggested that children are less affected than adults by SARS-CoV-2. We analyzed SARS-CoV-2 diagnoses between February 27, 2020, and March 14, 2020, and mortality among positive patients in Marseille university hospitals. Of 4050 tested individuals, 228 were positive. Deaths occurred in 2/99 documented cases (both > 85 year-old). Children were majorly asymptomatic. Incidence increased by 7.4-fold between 1-5 and 45-65 years then decreased. It was significantly lower among 0-1 year- (0%) and 1-5 (1.1%) and 5-10 (3.6%)-year-old children than among subjects > 18 years (6.5%). Viral loads did not differ between children and adults. Children may not contribute significantly to virus circulation.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Viral Load / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Eur J Clin Microbiol Infect Dis Journal subject: Communicable Diseases / Microbiology Year: 2020 Document Type: Article Affiliation country: S10096-020-03900-0

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Viral Load / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Eur J Clin Microbiol Infect Dis Journal subject: Communicable Diseases / Microbiology Year: 2020 Document Type: Article Affiliation country: S10096-020-03900-0