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Exploitation of Some Natural Products for the Prevention and/or Nutritional Treatment of SARS-CoV2 Infection.
Rizzo, Annalisa; Sciorsci, Raffaele L; Magrone, Thea; Jirillo, Emilio.
  • Rizzo A; Department of Veterinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
  • Sciorsci RL; Department of Veterinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
  • Magrone T; Department of Basic Medical Sciences, Neuroscience and Sensory Organs, University of Bari "Aldo Moro", School of Medicine, Bari, Italy.
  • Jirillo E; Department of Basic Medical Sciences, Neuroscience and Sensory Organs, University of Bari "Aldo Moro", School of Medicine, Bari, Italy.
Endocr Metab Immune Disord Drug Targets ; 21(7): 1171-1182, 2021.
Article in English | MEDLINE | ID: covidwho-740473
ABSTRACT
Dietary habits strongly influence our health status, mostly in terms of maintenance of the inflammatory/anti-inflammatory homeostasis. High fat and high sugar diets account for the development of a low-grade inflammation, which is the pathogenic common denominator of various chronic diseases. Severe Acute Respiratory Syndrome Coronavirus (SARS)-CoV2 (COVID-19) infection affects all ages and especially frail elderly people and a nutritional intervention seems to be crucial in the course of this pandemic. The present review describes the properties of some vegetal products and their derivatives, such as Lupin sp., garlic, salvia and extra virgin olive oil (EVOO) that can be exploited for their beneficial effects, as preventive and/or nutritional treatment of coronavirus disease SARS-CoV2. Lupin, salvia, garlic and EVOO share overlapping properties, such as anti-oxidant, anti-inflammatory and anti-viral activities. Quite importantly, these products and their derivatives are able to recover the expression of angiotensin converting enzyme expression 2 on cell membrane, otherwise suppressed by COVID-19 binding and entry into cytoplasm. Dietary administration of the above nutraceuticals or their extracts may play a preventive or nutritional role in the course of SARS-CoV2 infection, even including the effects of the lockdown and the condition of inflamm-ageing.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biological Products / Communicable Disease Control / Dietary Supplements / Diet Therapy / COVID-19 Type of study: Prognostic study Topics: Traditional medicine Limits: Humans Language: English Journal: Endocr Metab Immune Disord Drug Targets Journal subject: Allergy and Immunology / Endocrinology / Metabolism / Drug Therapy Year: 2021 Document Type: Article Affiliation country: 1871530320999200831231029

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biological Products / Communicable Disease Control / Dietary Supplements / Diet Therapy / COVID-19 Type of study: Prognostic study Topics: Traditional medicine Limits: Humans Language: English Journal: Endocr Metab Immune Disord Drug Targets Journal subject: Allergy and Immunology / Endocrinology / Metabolism / Drug Therapy Year: 2021 Document Type: Article Affiliation country: 1871530320999200831231029