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Considerations for Use of Hematopoietic Growth Factors in Patients With Cancer Related to the COVID-19 Pandemic.
Griffiths, Elizabeth A; Alwan, Laura M; Bachiashvili, Kimo; Brown, Anna; Cool, Rita; Curtin, Peter; Geyer, Mark B; Gojo, Ivana; Kallam, Avyakta; Kidwai, Wajih Z; Kloth, Dwight D; Kraut, Eric H; Lyman, Gary H; Mukherjee, Sudipto; Perez, Lia E; Rosovsky, Rachel P; Roy, Vivek; Rugo, Hope S; Vasu, Sumithira; Wadleigh, Martha; Westervelt, Peter; Becker, Pamela S.
  • Griffiths EA; 1Roswell Park Comprehensive Cancer Center, Buffalo, New York.
  • Alwan LM; 2Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance, Seattle, Washington.
  • Bachiashvili K; 3O'Neal Comprehensive Cancer Center at the University of Alabama, Birmingham, Alabama.
  • Brown A; 4University of Michigan Rogel Cancer Center, Ann Arbor, Michigan.
  • Cool R; 5The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Curtin P; 6UC San Diego Moores Cancer Center, La Jolla, California.
  • Geyer MB; 7Memorial Sloan Kettering Cancer Center, New York, New York.
  • Gojo I; 8The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
  • Kallam A; 9University of Nebraska Medical Center, Fred & Pamela Buffett Cancer Center, Omaha, Nebraska.
  • Kidwai WZ; 10Yale Cancer Center/Smilow Cancer Hospital, New Haven, Connecticut.
  • Kloth DD; 11Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Kraut EH; 12The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Columbus, Ohio.
  • Lyman GH; 2Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance, Seattle, Washington.
  • Mukherjee S; 13Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio.
  • Perez LE; 14Moffitt Cancer Center, Tampa, Florida.
  • Rosovsky RP; 15Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Roy V; 16Mayo Clinic Cancer Center; Jacksonville, Florida.
  • Rugo HS; 17UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California.
  • Vasu S; 12The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Columbus, Ohio.
  • Wadleigh M; 18Dana Farber/Brigham and Women's Cancer Center, Boston, Massachusetts; and.
  • Westervelt P; 19Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, Saint Louis, Missouri.
  • Becker PS; 2Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance, Seattle, Washington.
J Natl Compr Canc Netw ; : 1-4, 2020 Sep 01.
Article in English | MEDLINE | ID: covidwho-740554
ABSTRACT
Hematopoietic growth factors, including erythrocyte stimulating agents (ESAs), granulocyte colony-stimulating factors, and thrombopoietin mimetics, can mitigate anemia, neutropenia, and thrombocytopenia resulting from chemotherapy for the treatment of cancer. In the context of pandemic SARS-CoV-2 infection, patients with cancer have been identified as a group at high risk of morbidity and mortality from this infection. Our subcommittee of the NCCN Hematopoietic Growth Factors Panel convened a voluntary group to review the potential value of expanded use of such growth factors in the current high-risk environment. Although recommendations are available on the NCCN website in the COVID-19 Resources Section (https//www.nccn.org/covid-19/), these suggestions are provided without substantial context or reference. Herein we review the rationale and data underlying the suggested alterations to the use of hematopoietic growth factors for patients with cancer in the COVID-19 era.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: J Natl Compr Canc Netw Journal subject: Neoplasms Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: J Natl Compr Canc Netw Journal subject: Neoplasms Year: 2020 Document Type: Article