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Antibacterial Hybrid Hydrogels.
Cao, Zhongming; Luo, Yue; Li, Zhaoyang; Tan, Lei; Liu, Xiangmei; Li, Changyi; Zheng, Yufeng; Cui, Zhenduo; Yeung, Kelvin Wai Kwok; Liang, Yanqin; Zhu, Shengli; Wu, Shuilin.
  • Cao Z; Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Wuhan, 430062, China.
  • Luo Y; Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Wuhan, 430062, China.
  • Li Z; School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China.
  • Tan L; Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Wuhan, 430062, China.
  • Liu X; Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Wuhan, 430062, China.
  • Li C; Stomatological Hospital, Tianjin Medical University, Tianjin, 300070, China.
  • Zheng Y; College of Engineering, State Key Laboratory for Turbulence and Complex System, Department of Materials Science and Engineering, Peking University, Beijing, 100871, China.
  • Cui Z; School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China.
  • Yeung KWK; Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, 999077, China.
  • Liang Y; School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China.
  • Zhu S; School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China.
  • Wu S; School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China.
Macromol Biosci ; 21(1): e2000252, 2021 01.
Article in English | MEDLINE | ID: covidwho-740854
ABSTRACT
Bacterial infectious diseases and bacterial-infected environments have been threatening the health of human beings all over the world. In view of the increased bacteria resistance caused by overuse or improper use of antibiotics, antibacterial biomaterials are developed as the substitutes for antibiotics in some cases. Among them, antibacterial hydrogels are attracting more and more attention due to easy preparation process and diversity of structures by changing their chemical cross-linkers via covalent bonds or noncovalent physical interactions, which can endow them with various specific functions such as high toughness and stretchability, injectability, self-healing, tissue adhesiveness and rapid hemostasis, easy loading and controlled drug release, superior biocompatibility and antioxidation as well as good conductivity. In this review, the recent progress of antibacterial hydrogel including the fabrication methodologies, interior structures, performances, antibacterial mechanisms, and applications of various antibacterial hydrogels is summarized. According to the bacteria-killing modes of hydrogels, several representative hydrogels such as silver nanoparticles-based hydrogel, photoresponsive hydrogel including photothermal and photocatalytic, self-bacteria-killing hydrogel such as inherent antibacterial peptides and cationic polymers, and antibiotics-loading hydrogel are focused on. Furthermore, current challenges of antibacterial hydrogels are discussed and future perspectives in this field are also proposed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bacterial Infections / Hydrogels / Metal Nanoparticles / Anti-Bacterial Agents Type of study: Experimental Studies / Randomized controlled trials Limits: Humans Language: English Journal: Macromol Biosci Journal subject: Biochemistry Year: 2021 Document Type: Article Affiliation country: Mabi.202000252

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bacterial Infections / Hydrogels / Metal Nanoparticles / Anti-Bacterial Agents Type of study: Experimental Studies / Randomized controlled trials Limits: Humans Language: English Journal: Macromol Biosci Journal subject: Biochemistry Year: 2021 Document Type: Article Affiliation country: Mabi.202000252