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AmbuBox: A Fast-Deployable Low-Cost Ventilator for COVID-19 Emergent Care.
Fang, Zecong; Li, Andrew I; Wang, Hongcheng; Zhang, Ruoyu; Mai, Xiyan; Pan, Tingrui.
  • Fang Z; Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering, University of California, Davis, CA, USA.
  • Li AI; Department of Surgery, University of California Davis Medical Center (UCDMC), Sacramento, CA, USA.
  • Wang H; Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering, University of California, Davis, CA, USA.
  • Zhang R; School of Mechanical Engineering, Hangzhou Dianzi University, Hangzhou, China.
  • Mai X; Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering, University of California, Davis, CA, USA.
  • Pan T; Department of Electrical and Computer Engineering, University of California, Davis, CA, USA.
SLAS Technol ; 25(6): 573-584, 2020 12.
Article in English | MEDLINE | ID: covidwho-744955
ABSTRACT
We present a low-cost clinically viable ventilator design, AmbuBox, using a controllable pneumatic enclosure and standard manual resuscitators that are readily available (AmbuBag), which can be rapidly deployed during pandemic and mass-casualty events with a minimal set of components to manufacture and assemble. The AmbuBox is designed to address the existing challenges presented in the existing low-cost ventilator designs by offering an easy-to-install and simple-to-operate apparatus while maintaining a long lifespan with high-precision flow control. As an outcome, a mass-producible prototype of the AmbuBox has been devised, characterized, and validated in a bench test setup using a lung simulator. This prototype will be further investigated through clinical testing. Given the potentially urgent need for inexpensive and rapidly deployable ventilators globally, the overall design, operational principle, and device characterization of the AmbuBox system have been described in detail with open access online. Moreover, the fabrication and assembly methods have been incorporated to enable short-term producibility by a generic local manufacturing facility. In addition, a full list of all components used in the AmbuBox has been included to reflect its low-cost nature.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiration, Artificial / Ventilators, Mechanical / Emergency Medical Services / SARS-CoV-2 / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: SLAS Technol Year: 2020 Document Type: Article Affiliation country: 2472630320953801

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiration, Artificial / Ventilators, Mechanical / Emergency Medical Services / SARS-CoV-2 / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: SLAS Technol Year: 2020 Document Type: Article Affiliation country: 2472630320953801