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Clinical features and outcomes of seven patients with COVID-19 in a family cluster.
BMC Infect Dis ; 20(1): 647, 2020 Sep 03.
Article in English | MEDLINE | ID: covidwho-744977
ABSTRACT

BACKGROUND:

The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more details are needed about how family clusters cause the spread of coronavirus disease 2019 (COVID-19). CASE PRESENTATION We retrospectively reviewed 7 confirmed cases from one family cluster. Both clinical features and laboratory examination results were described. Patient 1 had been in close contact with someone who was later confirmed to have COVID-19 in Wuhan City before he returned back to his hometown. He had dinner with 6 other members in his family. All the persons developed COVID-19 successively except for one older woman who neither had dinner with them nor shared a sleeping room with her husband. Six patients had mild or moderate COVID-19 but one older man with underlying diseases progressed into the severe type. After general and symptomatic treatments, all the patients recovered.

CONCLUSIONS:

In a family cluster, having dinner together may be an important mode for the transmission of SARS-CoV-2. In this setting, most cases are mild with a favorable prognosis, while elderly patients with underlying diseases may progress into the severe type. For someone who has close contact with a confirmed case, 14-day isolation is necessary to contain virus transmission.
Subject(s)
Full text: Available Collection: International databases Database: MEDLINE Type: Article Main subject: Pneumonia, Viral / Family Health / Coronavirus Infections / Betacoronavirus Subject: Pneumonia, Viral / Family Health / Coronavirus Infections / Betacoronavirus Type of study: Case report / Observational study / Prognostic study / Risk factors Language: English Journal: BMC Infect Dis Year: 2020

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Full text: Available Collection: International databases Database: MEDLINE Type: Article Main subject: Pneumonia, Viral / Family Health / Coronavirus Infections / Betacoronavirus Subject: Pneumonia, Viral / Family Health / Coronavirus Infections / Betacoronavirus Type of study: Case report / Observational study / Prognostic study / Risk factors Language: English Journal: BMC Infect Dis Year: 2020