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Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology.
Zhang, Hao; Jiang, Xu-Jing; Liu, Xiao-Hua; Ma, Hong; Zhang, Ya-Hong; Rao, Yue; Li, Lin; Xu, Hai-Yan; Lyu, Fa-Jin.
  • Zhang H; Department of Radiology, Dianjiang People's Hospital of Chongqing, Chongqing, China.
  • Jiang XJ; Department of General Surgery, Dianjiang People's Hospital of Chongqing, Chongqing, China.
  • Liu XH; Department of Radiology, Dianjiang People's Hospital of Chongqing, Chongqing, China.
  • Ma H; Department of Oncology, Dianjiang People's Hospital of Chongqing, Chongqing, China.
  • Zhang YH; Department of Radiology, Changshou People's Hospital of Chongqing, Chongqing, China.
  • Rao Y; Department of Radiology, Zhongxian People's Hospital of Chongqing, Chongqing, China.
  • Li L; Department of Pharmacy, Dianjiang People's Hospital of Chongqing, Chongqing, China.
  • Xu HY; Department of Gastroenterology, Dianjiang People's Hospital of Chongqing, Chongqing, China.
  • Lyu FJ; Department of Radiology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
PLoS One ; 15(9): e0238760, 2020.
Article in English | MEDLINE | ID: covidwho-745057
ABSTRACT
In this study, we ascertained the chest CT data of 60 patients admitted to 3 hospitals in Chongqing with confirmed COVID-19. We conducted anatomical and pathological analyses to elucidate the possible reasons for the distribution, morphology, and characteristics of COVID-19 in chest CT. We also shared a semiquantitative scoring of affected lung segments, which was recommended by our local medical association. This scoring system was applied to quantify the severity of the disease. The most frequent imaging findings of COVID-19 were subpleural ground glass opacities and consolidation; there was a significant difference in semiquantitative scores between the early, progressive, and severe stages of the disease. We conclude that the chest CT findings of COVID-19 showed certain characteristics because of the anatomical features of the human body and pathological changes caused by the virus. Therefore, chest CT is a valuable tool for facilitating the diagnosis of COVID-19 and semiquantitative scoring of affected lung segments may further elucidate diagnosis and assessment of disease severity. This will assist healthcare workers in diagnosing COVID-19 and assessing disease severity, facilitate the selection of appropriate treatment options, which is important for reducing the spread of the virus, saving lives, and controlling the pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Tomography, Spiral Computed / Lung Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2020 Document Type: Article Affiliation country: Journal.pone.0238760

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Tomography, Spiral Computed / Lung Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2020 Document Type: Article Affiliation country: Journal.pone.0238760