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Coagulation and immune function indicators for monitoring of coronavirus disease 2019 and the clinical significance. / 2019冠状病毒病凝血和免疫功能指标的监测及临床意义.
Zhang, Junhua; Li, Tie; Huang, Rong; Gui, Rong; Chen, Sai.
  • Zhang J; Department of Blood Transfusion, Third Xiangya Hospital, Central South University, Changsha 410013. xy3zhangjunhua@csu.edu.cn.
  • Li T; Department of Laboratory Medicine, First People's Hospital of Yueyang, Yueyang Hunan 414000, China.
  • Huang R; Department of Blood Transfusion, Third Xiangya Hospital, Central South University, Changsha 410013.
  • Gui R; Department of Blood Transfusion, Third Xiangya Hospital, Central South University, Changsha 410013. aguirong@163.com.
  • Chen S; Department of Blood Transfusion, Third Xiangya Hospital, Central South University, Changsha 410013. 1754142340@qq.com.
Zhong Nan Da Xue Xue Bao Yi Xue Ban ; 45(5): 525-529, 2020 May 28.
Article in English, Chinese | MEDLINE | ID: covidwho-745331
ABSTRACT

OBJECTIVES:

To explore the significance of coagulation and immune function indicators in clinical diagnosis and treatment of coronavirus disease 2019 (COVID-19).

METHODS:

All patients with COVID-19 diagnosed and treated in First People's Hospital of Yueyang from January to March 2020 were enrolled. The general data of patients were collected. The patients were assigned into a light group (n=20), an ordinary group (n=33), a severe group (n=23), and a critically severe group (n=7) according to the severity of the disease. Coagulation and immune function indicators of each group were compared, and the relevance of coagulation and immune function indicators was analyzed.

RESULTS:

The age of COVID-19 patients in Yueyang City was mainly between 45 and 65 years old. There was a significant difference in the coagulation function and immune-related indicators in each group of patients (all P<0.05).

CONCLUSIONS:

There are some abnormalities in coagulation and immune function in patients with COVID-19, which possess significance for clinical diagnosis and treatment of the disease.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Coagulation / Coronavirus Infections Type of study: Diagnostic study / Prognostic study Limits: Aged / Humans / Middle aged Country/Region as subject: Asia Language: English / Chinese Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban Journal subject: Medicine Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Coagulation / Coronavirus Infections Type of study: Diagnostic study / Prognostic study Limits: Aged / Humans / Middle aged Country/Region as subject: Asia Language: English / Chinese Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban Journal subject: Medicine Year: 2020 Document Type: Article